Project Grant R01HD120576
- The National Institute of Child Health and Human Development, part of the Department of Health and Human Services National Institutes of Health, awarded $440,000 to the University of Texas Medical Branch at Galveston on August 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds research to evaluate mechanistic pathways through which heat exposure during pregnancy triggers preterm birth, addressing a knowledge gap in understanding...
- The National Institute of Child Health and Human Development awarded University of Maryland, College Park $515,009 on August 24, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to quantify the individual and combined effects of extreme heat and wildfire smoke exposure on hypertensive disorders of pregnancy and gestational diabetes mellitus. The research leverages a healthcare claims dataset encompassing approximately 6.5 million births during the...
- The National Institute of Child Health and Human Development awarded Trustees of Boston University $326,201 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to validate the Centers for Disease Control and Prevention–developed Severe Maternal Morbidity algorithm for identifying maternal near-miss cases in the obstetric population at Boston Medical Center, New England's largest safety-net hospital. The project addresses the urgent need...
- The National Institute of Child Health and Human Development awarded the University of Texas Health Science Center at Houston $688,009 on May 15, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate trophoblast differentiation and placental aging. The award funds research testing the hypothesis that precocious trophoblast differentiation leads to exhaustion of the trophoblast stem cell pool, triggering premature placental aging and...
- The National Institute of Child Health and Human Development awarded Boston College $654,483 under Project Grant R01HD117959 on September 15, 2025, through the Child Health and Human Development Extramural Research program (CFDA 93.865). Boston College will analyze Health Care Cost Institute patient claims data to quantify how state reproductive health policies before and after June 2022 affect maternal health outcomes and disparities. The research examines five outcomes: contraceptive use,...
- The National Institute of Child Health and Human Development awarded Duke University $694,448 on July 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct research analyzing local and global responses in the placenta syncytiotrophoblast. The research investigates the multinucleated syncytiotrophoblast, a giant single cell that separates maternal and fetal vasculature during pregnancy and performs critical functions including nutrient...
- The National Institute of Child Health and Human Development awarded The General Hospital Corporation (Massachusetts General Hospital) $443,954 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a four-year mixed-methods assessment of obstetric readiness in low-resource emergency departments. The research addresses the clinical gap created by closures of labor and delivery units that leave 2.3 million women of childbearing age in...
- The National Institute of Child Health and Human Development, part of the Department of Health and Human Services National Institutes of Health, awarded $456,500 to The University of Texas Southwestern Medical Center on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds molecular characterization of human pregnancy-induced cervical epithelium through two research aims. First, the recipient will apply single-cell and spatial...
- The National Institute of Child Health and Human Development awarded $668,485 to the University of California, San Diego on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate DNA repair mechanisms in hypoxia-induced placental genomic instability. The research examines increased genomic instability in placental villous tissue and trophoblast stem cells associated with maternal vascular malperfusion, a pattern of placental...
- The National Institute of Child Health and Human Development awarded the University of Washington $564,830 on June 15, 2026, under the Child Health and Human Development Extramural Research Projects program (CFDA 93.HDR) to investigate sex differences in allelic gene regulation in human placenta. The research examines how sex chromosome dosage influences allelic gene regulation during placental development and trophoblast differentiation. The project determines whether sex chromosome...
The National Institute of Child Health and Human Development awarded Boston University (Trustees of Boston University, doing business as Boston University Medical Campus) $702,577 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a longitudinal study examining heat exposure, placental health, and adverse pregnancy outcomes. The research leverages an existing cohort of 610 pregnant women who attended prenatal visits at Eastern Virginia Medical School and the University of Texas Medical Branch during 2016–2020 and previously had their placental development and function measured at up to eight visits throughout pregnancy under NICHD's Human Placenta Project. The study links participant address data to spatiotemporally resolved meteorologic datasets to estimate gestational week-specific measures of extreme heat exposure and assess the effects of ambient temperature throughout pregnancy on repeated measures of placental, maternal, and fetal health. The central hypothesis is that exposure to high ambient temperatures impairs placental development and function, with downstream effects on adverse pregnancy and birth outcomes. Place of performance is Roxbury, Massachusetts. The period of performance runs from September 1, 2026, through May 31, 2031. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $702.6k | 8/26/26 |