Project Grant R01HD120421
- The National Institute of Neurological Disorders and Stroke awarded Cincinnati Children's Hospital Medical Center $228,420 on September 1, 2026, under the K23 career development grant program to support research quantifying motor network dynamics in pediatric dystonia. The award funds a five-year physician-scientist training and research initiative running through August 31, 2031. The candidate will develop brain-based biomarkers to guide and optimize treatment for children with dystonia by...
- The National Institute of Neurological Disorders and Stroke awarded Virginia Commonwealth University $173,335 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and validate clinical outcome assessments for congenital myotonic dystrophy in children. The project addresses gaps in measuring motor function change in congenital myotonic dystrophy (CDM), a severe inherited disorder characterized by progressive...
- The National Institute of Child Health and Human Development awarded the University of Washington $616,250 on September 1, 2026, through the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a randomized controlled trial evaluating non-invasive spinal cord stimulation combined with intensive treadmill training to reduce spasticity and improve mobility in children with cerebral palsy. The research will enroll children with cerebral palsy in a 24-session...
- The National Institute of Child Health and Human Development awarded the University of Washington $647,235 on July 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to evaluate a developmental powered mobility intervention for young children with cerebral palsy. The award funds a randomized clinical trial of the Developmental Power Mobility (DPM) intervention, which leverages an FDA-cleared Explorer Mini device to address mobility limitations in...
- The National Institute of Child Health and Human Development awarded The Children's Hospital Corporation (doing business as Boston Children's Hospital) $431,781 on July 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the impacts of genetic testing in individuals with cerebral palsy. The project will examine family perspectives on the psychosocial impact and utility of genetic testing for cerebral palsy, assess whether a genetic...
- The National Institute of Child Health and Human Development awarded The Children's Hospital of Philadelphia $482,901 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop precise measurement approaches for selective motor control impairment in children with cerebral palsy. The research characterizes patterns of impaired motor control in cerebral palsy using electromyography paired with biofeedback during single-joint movement...
- The National Institute of Child Health and Human Development awarded the University of Washington $383,200 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to optimize transcutaneous spinal cord stimulation intensity for gait training in children with cerebral palsy. The research systematically evaluates how varying spinal stimulation intensities affect gait biomechanics in ambulatory children with bilateral cerebral palsy. In the first aim,...
- Federal Grant Award Summary The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $472,325 Project Grant to the Rehabilitation Institute of Chicago (doing business as Shirley Ryan AbilityLab) on August 4, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The project, "Quantifying Selective Motor Control in Preterm Infants: A Computer Vision Approach," will develop and validate a computer...
- The National Institute of Neurological Disorders and Stroke awarded Washington University $427,625 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and evaluate induced pluripotent stem cell (iPSC)-derived models of Mitchell syndrome, a rare progressive childhood-onset neurodegenerative disorder. Washington University will generate two scalable, disease-relevant human cell models—iPSC-derived oligodendrocytes...
- The National Institute of Child Health and Human Development, part of the National Institutes of Health, awarded the University of Illinois $110,228 on December 3, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop a markerless motion-capture tool for objectively evaluating motor impairments in stroke survivors. The project, titled "Action Likelihood to Evaluate Weakness, Abnormal Motor Synergies, and Spasticity in Stroke Survivors,"...
The National Institute of Child Health and Human Development awarded Washington University $667,506 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to develop a caregiver-reported dystonia impact scale for children with cerebral palsy. The project addresses underdiagnosis of dystonia in cerebral palsy, a condition affecting 1 in 500 people in the United States. Dystonia commonly causes motor functional limitations in childhood but is difficult to evaluate in clinics because it co-occurs with spasticity; missed dystonia can lead to unnecessary surgeries or prevent targeted treatment. Existing clinician-administered dystonia severity scales are time-consuming, lack responsiveness data in cerebral palsy populations, and miss functionally impactful dystonia. The award funds creation of a caregiver-reported assessment tool that does not depend on caregivers' prior knowledge of dystonia. Preliminary data show that yes-or-no caregiver responses to two questions about triggered involuntary movements can identify dystonia with 75 percent sensitivity and 81 percent specificity, and that asking caregivers about variable movements in clinic can improve dystonia diagnostic rates from 57 percent to 74 percent of children with cerebral palsy, aligning with research-based prevalence estimates. Performance occurs at Washington University's St. Louis, Missouri location. The award period runs September 1, 2026, through August 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $667.5k | 9/2/26 |