Project Grant R01HD120282
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $237,827 to Brigham & Women's Hospital Inc. to develop a wearable, non-invasive optical device for continuous blood pressure monitoring in neonates. The device, called CNAP-FlexNIRS, will use near-infrared spectroscopy and photoplethysmography to collect high-resolution pulsatile waveforms and...
- The National Institute of Child Health and Human Development (NICHD), through the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865), awarded a $584,317 project grant to The General Hospital Corporation (doing business as Massachusetts General Hospital) to validate and optimize their non-invasive fetal sequencing (NIFS) technology. This technology aims to enable unbiased fetal exome screening at high coverage from a maternal blood draw, which could...
- This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $318,724 to Pendar Technologies LLC to develop and test an optical probe for monitoring peripheral tissue oxygenation in critically ill neonates. The award will fund improvements to the company's resonance Raman spectroscopy-based sensor technology, which can measure tissue oxygen saturation...
- The National Institute of Child Health and Human Development (NICHD) awarded a $624,998 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Giner Inc. of Auburndale, Massachusetts. The award will fund the development and validation of an electrochemical assay and point-of-care instrument for highly sensitive, near-real-time perinatal monitoring of oxytocin levels. Oxytocin is a critical neuropeptide hormone for facilitating childbirth and...
- The National Institute of Child Health and Human Development (NICHD), through its Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865), awarded a $306,669 Project Grant to Enhance Diagnostics, Inc. on September 15, 2025. The grant will support the development of a simple, non-invasive breath test to monitor blood ammonia levels in individuals with Urea Cycle Disorders (UCDs), a rare inherited metabolic condition. The technology aims to provide a quick,...
- The Children's Hospital Corporation, doing business as Boston Children's Hospital, received a $584,406 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865). The grant, awarded on September 1, 2025, will fund the development of motion-robust 3D Kooshball data acquisition and advanced reconstruction strategies for rapid high-resolution quantitative...
- This Project Grant award, with a total funding amount of $658,761.00, was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Federal Grant Program (CFDA 93.865). The project aims to develop a deep learning model that can improve the interpretation of electronic fetal monitoring (EFM) data to better predict fetal acidemia and reduce unnecessary obstetric interventions. The...
- This Project Grant award of $371,021 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of a continuous respiratory monitoring platform to better classify apnea of prematurity (AOP) in premature newborns. The primary products to be delivered are: 1) a multimodal system and machine learning model to accurately detect and classify the major types of AOP (central, obstructive, and mixed); and 2) an optimized prototype system...
- The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research CFDA program (93.837), awarded a $483,852 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop a platform technology for measuring the kinetics and equilibrium concentration of sickle hemoglobin polymerization in single red blood cells. This technology aims to support drug potency assessment and patient risk stratification for sickle...
- The National Institute of Child Health and Human Development (NICHD) awarded a $434,500 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Research Institute at Nationwide Children's Hospital. The grant, titled "NEOGX-III: Interpretable Machine Learning with Integrated Analysis of Maternal & Infant Electronic Medical Records for Unbiased Prediction of Need for Genome Sequencing in Level III NICUs," aims to develop a machine...
The federal Project Grant award of $2,453,962.00, awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to develop a noninvasive neonatal blood gas monitoring system. The research, conducted by The General Hospital Corporation (doing business as Massachusetts General Hospital), aims to address the challenges of frequent blood gas testing for critically-ill infants in neonatal intensive care units (NICUs). The project seeks to create a new technology that can continuously monitor blood oxygen and carbon dioxide levels without the need for repeated blood draws, which can lead to blood loss and other complications in premature and seriously ill newborns. The award, with a performance period from August 2025 to July 2029, will fund the development and testing of this innovative, noninvasive blood gas monitoring solution to improve care for vulnerable neonatal patients.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.5m | 8/7/25 |