Project Grant R01HD117940
Award Date
7/1/25
Completion Date
5/31/30
Dollars Obligated
$696K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Arkansas, USA
Similar Awards
This federal Project Grant award of $2,519,726.00, provided by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), aims to analyze the pharmacokinetics, pharmacogenetics, and clinical utility of the triple combination therapy (TC) elexacaftor/tezacaftor/ivacaftor for cystic fibrosis (CF) patients. The study, titled "ENSURING ACCESS TO OPTIMAL THERAPY IN CF: ENACT STUDY," will: Analyze the population pharmacokinetics of the TC compounds in...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $501,003 to the University of Utah to conduct research on optimal dosing of common asthma medications for pregnant individuals. The primary objectives are to: 1) develop physiologically-based pharmacokinetic (PBPK) models for two asthma drugs to understand how pregnancy affects their...
The National Institute of Child Health and Human Development (NICHD) awarded a $743,287 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Oregon Health & Science University (OHSU) to conduct a multi-disciplinary study aimed at uncovering novel insights into endocervical mucus secretion. The goal of the project is to better understand how female sex hormones regulate the biophysical properties of endocervical mucus, with the long-term objective of...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $190,163 to the University of Utah to develop a Pediatric Clinical Pharmacology Training Program. The goal is to train clinician-scientists and Ph.D. researchers as leaders in the field of pediatric and maternal clinical pharmacology research. The program will leverage the university's expertise in...
This Project Grant award, with the federal grant ID R01HD114750, was provided by the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $2,018,716 award, with a project period from June 2024 to March 2029, will support research to investigate the hormonal and ionic mechanisms regulating uterine fluid absorption during early pregnancy. The research aims to use mouse models and human endometrial...
The federal Project Grant award R21HD111905, with a total funding of $234,000.00, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The primary awardee, The Regents of the University of Colorado (University of Colorado-Denver), will conduct research to investigate the functional importance of a novel NF-kB genetic variant (rs230511) and its role in the development of...
This $178,000 federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to create early life phenotypes of very preterm infants. The goal is to use perinatal variables, such as reason for birth, intrapartum care, and neonatal presentation, to categorize infants into distinct phenotypes that can explain variation in later health outcomes, including...
This $1,538,070 federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the mechanisms by which glucose and glutamine metabolism regulate trophoblast differentiation and placental development. The awardee, the Regents of the University of Minnesota, will use CRISPR-Cas9 genetic tools to manipulate the expression of the...
This $158,216 federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports a longitudinal study on the impacts of prenatal exposure to maternal incarceration on infant and toddler health and development. The research, conducted by the Harvard T.H. Chan School of Public Health, will use mixed-methods analysis to assess how maternal experiences before and...
This $219,592 Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to develop novel designed multi-ligand (DML) drugs that target dysregulated pathways in preterm myometrium to provide therapeutic benefit in cases of preterm labor. The research aims to generate DML drugs that can effectively delay or halt early labor and prevent preterm birth,...