Project Grant R01HD116825
Award Date
6/1/25
Completion Date
2/28/30
Dollars Obligated
$486K
Federal Agency
National Institute of Child Health and Human Development
Federal Grant Program
93.865
Assistance Type
Project Grant
Place of Performance
Tempe, AZ 85287, USA
Similar Awards
The National Institute of Child Health and Human Development (NICHD) awarded a $136,916 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the Louisiana State University Agricultural Center to develop a computational model for predicting the morphology, patterning, and strength of regenerated bone in small animal models of limb regeneration. The project aims to create new tools to better evaluate the structural quality and function of regenerated bone,...
This $420,883 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research to improve muscle regeneration and restore function following serious traumatic injuries. The University of Missouri System, the prime recipient, will leverage its expertise in microvascular imaging, muscle biology, and biomaterials to investigate the role of fibroadipogenic...
This $1,633,451 federal Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) will fund a research project at Texas A&M AgriLife Research to determine the cell-specific mechanisms driving aberrant bone regeneration in Down syndrome. The 3-year project aims to characterize the transcriptome, osteoclast/osteoblast activity, and sexually dimorphic impacts on bone healing in multiple murine models of Down syndrome. The research will...
This Project Grant award from the National Institute of Child Health and Human Development (CFDA 93.865 - Child Health and Human Development Extramural Research) provides $294,408 to the University of Oregon (UO) to conduct research on how cell signaling mediates skeletal patterning during zebrafish fin regeneration. The research aims to identify key genes and cell behaviors regulated by sonic hedgehog signaling that promote interactions between basal epidermal cells and progenitor...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $270,000.00 to The Morgridge Institute for Research, Inc. to conduct research on spinal cord regeneration in zebrafish. The key objectives are to: 1) elucidate cell state changes associated with successful versus failed spinal cord regeneration in zebrafish, and 2) define and manipulate the...
This $1,192,487 five-year Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program will support research to uncover the cellular and molecular mechanisms governing tissue regeneration in the model organism Drosophila melanogaster. The key objectives are to investigate: (i) the processes that activate and sustain the regenerative microenvironment, (ii) the gene regulatory networks driving distinct...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286) aims to develop a translational strategy for sequentially delivering bone morphogenetic proteins BMP2 and BMP9 using magnetic microgels. The goal is to spatiotemporally control bone and joint formation after digit amputation to promote progenitor cell-mediated...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is providing $435,875.00 to the University of Texas at Austin to develop robust and accessible methods for non-invasive quantification of the mechanical properties of cell-cell junctions and the cytoplasm in vertebrate embryos. The goal is to improve the depth and breadth of understanding of embryo biomechanics...
This $1,174,440.00 federal Project Grant award, funded by the National Science Foundation (NSF) Division of Integrative Organismal Systems (CFDA 47.074 Biological Sciences), supports collaborative research to identify the shared genetic and cellular mechanisms underlying vertebrate limb and fin regeneration. The research team at Louisiana State University, the prime awardee, is using a comparative approach across three animal models - salamanders, lungfish, and Polypterus - to uncover the core...
This Project Grant award, valued at $387,500.00 and funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859), supports research focused on understanding the gene regulatory networks involved in hair cell regeneration in zebrafish. The primary awardee, The Johns Hopkins University, will conduct studies to elucidate how the SOX and SIX families of transcription factors control hair cell regeneration, as well as...