This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $388,575.00 to Rutgers, The State University for a 2-year research project from August 2024 to July 2026. The project aims to develop a novel platform for encapsulating bioactive proteins, such as Bone Morphogenic Protein 2 (BMP-2), within hydrophobic polymer...
This federal Project Grant award of $454,050.00 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA Program 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research will fund the development of a novel gene therapy for bone healing based on adeno-associated virus (AAV) delivery of bone morphogenetic protein-2 (BMP-2). The research aims to create an effective, affordable, and clinically expedient treatment for healing critical size osseous...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $1,582,671 Project Grant under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA 93.286) program to the University of Connecticut (UConn) to develop a novel "bionic bone composite scaffold" (BBCS) for regenerating large bone defects without the use of stem cells, growth factors, or other biologics. The BBCS is designed to be a fully biodegradable,...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the CFDA program "Discovery and Applied Research for Technological Innovations to Improve Human Health" (CFDA #93.286) is funding research to develop an injectable, self-powered piezoelectric scaffold to treat osteoarthritis in large animal models. The $597,683 award supports the University of Connecticut's efforts to create a new injectable piezoelectric nanocomposite hydrogel...
This $113,932 federal Project Grant award, issued on January 15, 2025 by the National Science Foundation (NSF) under the CFDA 47.049 Mathematical and Physical Sciences program, supports the development of a novel magnetoelectric biomaterial for bone tissue engineering at Boise State University. The project aims to create 3D-printed porous bioscaffolds that mimic the properties of natural human bones, including their mechanical strength, elasticity, and ability to generate electrical stimuli....
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) is focused on understanding the role of mechanical load in mammalian digit regeneration. The $485,782 award to Texas A&M AgriLife Research aims to determine how mechanical load regulates various aspects of appendage regeneration, with the ultimate goal of informing targeted therapies for inducing...
This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund the development and validation of a regenerative "intelligent" biorobot for the treatment of volumetric muscle loss (VML) injuries. The $616,256 award to Cleveland State University will support the creation of a piezoelectric biorobot that can deliver myoblasts and...
This federal Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) provides $295,000 to support the design, development, and testing of a novel implantable system that leverages distraction osteogenesis as a treatment for diabetic foot ulcers. The project aims to develop a low-profile implantable device with an active mechanical mechanism to transversely distract or retract a cut tibia bone segment in a programmable...
This $600,475 federal Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research) aims to develop a collagen-based scaffold modified with specific integrin ligands and placental mesenchymal stem cell-derived extracellular vesicles. This engineered scaffold is intended to synergistically recruit and guide endogenous stem cells for vascularized bone regeneration in utero to...
This $476,886 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research at Boston University to develop computational models for predicting the spatiotemporal distribution of growth factors in tissue engineering scaffolds. The goal is to optimize scaffold designs to achieve optimal growth factor exposure profiles that improve tissue regeneration outcomes, particularly for cartilage repair. The research utilizes reaction-diffusion...