This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $378,123 to the Research Foundation of the City University of New York (RFCUNY) over a period of approximately 3 years. The funding supports research aimed at identifying and testing mechanisms that establish the transcriptional regulatory potency of early embryos. Key research activities...
This federal Project Grant award, with ID F31HD113347, is funded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research (CFDA 93.865) program. The award, totaling $160,877, supports research on the role of histone demethylase enzymes in the development of primordial germ cells during mouse embryonic development. The research aims to elucidate the mechanisms of epigenetic remodeling, including the removal of...
The National Institute of Child Health and Human Development (NICHD) awarded a Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the Whitehead Institute for Biomedical Research. The $271,728 grant, awarded on September 15, 2024, will support research to uncover the molecular mechanisms that initiate and maintain germ cell identity. The research aims to (a) discover the dynamics of germline gene activation during embryogenesis, (b) identify...
This is a Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award is for $125,000 and will run from April 1, 2025 to March 31, 2027. The purpose of this grant is to develop spatially-resolved, integrated cell state and lineage tracing technologies to study progenitor cell dynamics during early mouse development. The awardee, the Whitehead Institute for...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to quantitatively understand how the Nodal signaling pathway and its inhibitors, cofactors, and coreceptors function in regulating cell fate patterns during embryonic development. The research will be conducted by William Marsh Rice University, located in Houston, Texas, and will leverage...
The National Institute of Child Health and Human Development (NICHD) awarded a $104,838 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Duke University to conduct research on the BMP signaling pathway and its role in embryonic development. The research program will employ cutting-edge quantitative live imaging techniques, mathematical modeling, and tools for studying BMP signaling in diverse insect species to shed light on how cells perceive and respond to...
This federal Project Grant award, valued at $179,564.00 and provided by the National Institutes of Health (NIH) through the Child Health and Human Development Extramural Research program (CFDA 93.865), supports a research project to enhance the understanding of human-specific mechanisms governing embryonic development during the implantation stage. The project aims to investigate the role of Wnt/β-catenin signaling and its impact on epiblast tissue remodeling across different mammalian...
This federal Project Grant award of $1,204,928 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to investigate the mechanisms by which rare genetic variants in regulatory enhancer regions can cause ectopic gene expression and developmental disorders, using limb malformations as a model. The key objectives of the award are to: 1) characterize the chromatin and...
This federal Project Grant award of $205,625 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to study the role of the RNA methyltransferase NSUN2 in regulating translation and pluripotency in stem cells. The research will identify NSUN2-modified RNA targets and understand how they are regulated at the translational level to control stem cell pluripotency, a fundamental...
The federal Project Grant award, ID K99HD115830, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $132,705 grant will fund a study to investigate the neural mechanisms underlying developmental delays in premature and full-term infants. The 2-year project, set to run from July 2024 to June 2026, will use electroencephalography (EEG) to longitudinally assess brain...