Project Grant R01HD116112
- This federal Project Grant award of $155,348 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to analyze sex-dependent differences in zebrafish fin regeneration. The primary objectives are to collect, analyze, and report phenotypic and transcriptomic data by sex during the fin regeneration process. The project seeks to reveal both sex-dependent and...
- This $409,750 Project Grant was awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research Program (CFDA 93.865). The grant supports research to discover mechanisms by which the neurotransmitter serotonin (5-HT) controls spine morphology and spinal deformities, such as adolescent idiopathic scoliosis. Using the zebrafish model, the research project aims to determine when and where 5-HT...
- This $114,458 Project Grant was awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Duke University. The grant supports quantitative research into how zebrafish appendages regenerate original size and function after injury. Specifically, the research aims to dissect how zebrafish tissue encodes "size memory" during appendage regeneration and how signaling dynamics in...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research federal grant program (CFDA 93.865), provides $561,640 to Duke University to conduct research on the signaling and cellular mechanisms underlying notochord patterning in zebrafish. The goal of this 5-year project is to integrate genetics, cell biology, and quantitative imaging methods to investigate the...
- This $294,408 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research at the University of Oregon to further understand how cell signaling mediates cell-cell interactions to facilitate intricate skeletal patterning during zebrafish fin regeneration. The research aims to identify the key Sonic Hedgehog (SHH) signaling target genes...
- This $156,080 Project Grant was awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant was awarded to Oregon Health & Science University (UEI: NPSNT86JKN51) to conduct research aimed at identifying the factors that define neural stem cells (NSCs) in the spinal cord and their role in regenerating the central nervous system (CNS) in response to...
- This Project Grant award in the amount of $386,100.00 was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant supports research to investigate the role of ectopic X-chromosome inactivation in limb patterning and development. The research aims to uncover the spatial-temporal landscape of gene suppression by ectopic X-chromosome inactivation and...
- This $687,427 Project Grant awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Federal Grant Program 93.865 - Child Health and Human Development Extramural Research, aims to investigate the role of macrophages in guiding digit regeneration. The project leverages a comparative mouse model of bone regeneration and scar formation to study a unique population of macrophages that associates with growing bone and expresses growth factors...
- This $270,000 project grant, awarded by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to define the inherent regenerative capacity of the zebrafish spinal cord. The research seeks to understand the molecular signals that enable or inhibit spinal cord regeneration, with the goal of shifting the mammalian spinal cord injury response from scarring to regeneration. The work, to be...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $595,864 Project Grant to the Magee-Womens Research Institute and Foundation in Pittsburgh, PA, effective August 15, 2025 and scheduled for completion on May 31, 2030. The grant, awarded under the NICHD's Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to elucidate the role of hyaluronan, a key extracellular matrix component, in the development...
This $424,074 Project Grant was awarded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Rutgers, The State University in New Jersey. The grant will fund a 5-year research project to investigate the functional roles of diverse embryonic cell populations in the formation of the shoulder girdle skeleton, using the zebrafish as a model system. Key objectives include determining how bone-forming osteoblasts differentiate from distinct embryonic origins and how this embryonic heterogeneity contributes to variation in skeletal morphology. The project will leverage advanced genomic, genetic, and imaging techniques to dissect the regulatory mechanisms underlying this process, with a focus on the role of the Gli transcription factor in chromatin accessibility and osteoblast differentiation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $424.1k | 8/11/25 |