Project Grant R01EY038797
- The National Eye Institute awarded The Schepens Eye Research Institute Inc. $506,030 on September 1, 2026, under the Vision Research program (CFDA 93.867) to develop an open-source solution for exporting and integrating optical coherence tomography data across institutions. The project addresses a critical barrier in ophthalmic research: OCT imaging data from multiple manufacturers is stored in over ten proprietary, undocumented formats with export tools that are prohibitively slow—exporting a...
- The National Eye Institute of the Department of Health and Human Services awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $723,931 on August 15, 2026, under the Vision Research program (CFDA 93.867). The award funds functional characterization of lateral geniculate nucleus (LGN) microstimulation as an advanced artificial vision system. The research validates a novel 1000-channel electrode array called the Fountain Probe, engineered for volumetric...
- The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $643,357 on June 15, 2026, under the Vision Research program (CFDA 93.867) to develop a Brillouin microscopy-based imaging method for direct, high-resolution measurement of corneal hydration. The project aims to create a combined Brillouin–optical coherence tomography system to map corneal...
- Federal Project Grant Award Summary Kineolabs, Inc. received a $300,001 Project Grant from the National Eye Institute (NEI) under the Vision Research program (CFDA 93.867) to develop a portable, low-cost line-scan swept-source optical coherence tomography imaging system (LS-SS-OCT). The system is designed for early detection and monitoring of age-related macular degeneration (AMD), diabetic retinopathy, and other eye diseases. The one-year project, which commenced July 1, 2025 and concludes June...
- The National Eye Institute awarded Oregon Health & Science University $498,180 on September 1, 2026, under the Vision Research program (CFDA 93.867) to develop and apply novel optical coherence tomography (OCT) methods for detecting and monitoring photoreceptor changes associated with age-related macular degeneration. The project runs through August 31, 2030, with performance based in Portland, Oregon. Aim 1 investigates cone photoreceptor function impairments in AMD through advancement of...
- The National Eye Institute awarded The Schepens Eye Research Institute $858,394 on August 1, 2026, under the Vision Research program (CFDA 93.867) to develop multimodal foundation models for eye disease screening and prognosis. The research develops a vision-language foundation model trained on pairs of retinal images and clinical notes to enable downstream supervised models for detection and progression prediction of age-related macular degeneration, diabetic retinopathy, and glaucoma. The...
- The National Eye Institute awarded Oregon Health & Science University $237,341 on August 1, 2026, to develop curvature and color correction techniques for ultrawidefield optical coherence tomography imaging of the retina under the Vision Research program (CFDA 93.867). The project addresses fundamental limitations in current OCT technology by applying GPU-accelerated ray tracing for geometric reconstruction of the retina to eliminate distortion and curvature artifacts in widefield imaging,...
- The National Eye Institute awarded Bluebird Photonics, Inc., $611,706 on September 30, 2025, under the Vision Research program (CFDA 93.867) to develop a novel stretched-pulse-mode-locking (SPML) laser for optical coherence tomography (OCT) imaging of the retina. This Phase I Small Business Technology Transfer award funds refinement of the SPML laser design and advancement from prototype to a turn-key, environmentally robust commercial instrument. The project includes implementation of a...
- Federal Project Grant Award Summary Award Overview Massachusetts General Hospital received a $453,750 Vision Research (CFDA 93.867) Project Grant from the National Eye Institute, effective September 1, 2025, through August 31, 2027. The award supports fundamental neuroscience research aimed at characterizing the cellular architecture and genetic organization of the lateral geniculate nucleus (LGN), a critical visual processing center in the brain. Research Products and Services The project...
- The National Eye Institute, National Institutes of Health, awarded $1.234892 million to Intelon Optics, Inc. on September 15, 2025, under the Vision Research program (CFDA 93.867) to develop a next-generation Brillouin Optical Scanner System (BOSS) with improved speed, accuracy, and sensitivity for ocular biomechanics measurement. The project will translate research technology developed by Dr. Scarcelli at the University of Maryland into a commercially viable clinical device capable of detecting...
The National Eye Institute awarded $753,787 to The General Hospital Corporation (doing business as Massachusetts General Hospital) on August 1, 2026, under the Vision Research program (CFDA 93.867) to develop low-cost ultra-widefield retinal optical coherence tomography (OCT) technology based on photonic-electronic integration. The project addresses cost barriers that limit clinical availability of OCT instrumentation used to detect and monitor diabetic retinopathy, age-related macular degeneration, and glaucoma. The funded work will fabricate complete OCT engines using active photonic integrated circuits based on thin-film lithium niobate (TFLN), incorporating a light source, optical interferometer, and output signal detectors. The research encompasses five aims: development of an OCT light source on a TFLN photonic integrated circuit (Aims 1–2); creation of the interferometer and receiver on a TFLN-PIC (Aim 3); development of an application-specific integrated circuit driver to enable A-scan speeds greater than 700 kilohertz (Aim 4); and demonstration of full-speed imaging in a human subject pilot study (Aim 5). The work combines efforts from three research groups led by Dr. Vakoc (principal investigator), Dr. Loncar, and Dr. Hills. Performance occurs in Massachusetts. The award period runs August 1, 2026, through July 31, 2030. This is a project grant, the standard assistance type for investigator-initiated research under the Vision Research program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $753.8k | 7/21/26 |