Project Grant R01EY038077
- The National Eye Institute awarded the Board of Regents of the University of Nebraska, through its University of Nebraska Medical Center division, $383,750 on September 1, 2026, under the Vision Research program (CFDA 93.867) to investigate oxidative stress and NLRP3 inflammasome activation in eye lens pathobiology during aging. The research examines molecular pathways linking reactive oxygen species amplification, dysregulation of antioxidant defenses, and inflammasome-driven inflammatory...
- The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded $693,423 to the University of Mississippi Medical Center on September 15, 2025, under the Vision Research program (CFDA 93.867) to develop and test a multivalent antibody cocktail for treating and preventing bacterial endophthalmitis. The funded research combines eight antibodies targeting virulence factors of Staphylococcus epidermidis, Staphylococcus aureus, and...
- The National Eye Institute awarded the University of Mississippi Medical Center $584,806 on August 1, 2026, under the Vision Research program (CFDA 93.867) to investigate mechanisms of adhesion and colonization during pneumococcal keratitis caused by Streptococcus pneumoniae. The research examines how pneumococcal bacteria regulate their outer polysaccharide capsule to adhere and colonize the corneal surface, and identifies a master regulatory system that controls bacterial survival and...
- The National Eye Institute, a bureau of the Department of Health and Human Services National Institutes of Health, awarded $497,740 to the University of Illinois on April 1, 2026, under the Vision Research program (CFDA 93.867) to fund research into neuro-epithelial interactions in corneal disease and repair, with Principal Investigator Elmira Jalilian. The project investigates how corneal epithelial cells and trigeminal nerve fibers (the V1 ophthalmic branch) interact to maintain corneal...
- The National Eye Institute, part of the National Institutes of Health within the Department of Health and Human Services, awarded Creighton University $350,000 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to support discovery and development of novel trifunctional hybrid compounds for glaucoma therapy. The funded research focuses on designing and evaluating trifunctional hybrid compounds that integrate three disease-modifying entities—an FP...
- The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded $628,100 to the University of Miami on May 1, 2026, under the Vision Research program (CFDA 93.867) to advance understanding of lens remodeling in childhood myopia development and progression. The project will develop new technologies to measure three-dimensional lens shape, ocular biometry, central and peripheral refraction, and accommodation-related changes in children. The...
- The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded The Johns Hopkins University $110,228 on February 12, 2027, under the Vision Research program (CFDA 93.867) to conduct research on the mediation of oculomotor learning by the cerebellar cortex. The funded research investigates how molecular layer interneurons and Purkinje cells within the cerebellar cortex's oculomotor vermis adapt rapid eye movements (saccades) in response to...
- The National Eye Institute, part of the National Institutes of Health, awarded the University of New Mexico Health Sciences Center $350,000 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate neutrophil extracellular traps and chemokine signaling in blood-retinal barrier disruption in diabetic retinopathy. The funded research targets mechanisms underlying diabetic retinopathy, the leading cause of vision loss in middle-aged adults....
- The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded $2,271,828 to The University of Texas Southwestern Medical Center on September 1, 2026, under the Vision Research program (CFDA 93.867). The recipient will conduct research into the cellular and molecular mechanisms governing optic nerve myelin integrity, with emphasis on understanding how myelin whorls—multilayered degenerative myelin structures that appear in demyelinating...
- The National Eye Institute awarded The Schepens Eye Research Institute $858,394 on August 1, 2026, under the Vision Research program (CFDA 93.867) to develop multimodal foundation models for eye disease screening and prognosis. The research develops a vision-language foundation model trained on pairs of retinal images and clinical notes to enable downstream supervised models for detection and progression prediction of age-related macular degeneration, diabetic retinopathy, and glaucoma. The...
The National Eye Institute, part of the Department of Health and Human Services National Institutes of Health, awarded the Board of Regents of the University of Nebraska (University of Nebraska Medical Center) $1,267,127 on August 1, 2026 for Project Grant R01EY038077, funded under the Vision Research program (CFDA 93.867). The award funds clinical and molecular biomarker surveillance of mpox-related ocular disease. The research characterizes the spectrum of ophthalmic manifestations of mpox clade I and clade II infection, focusing on keratitis, conjunctivitis, and uveitis. The recipient will assess the kinetics of mpox DNA tear film clearance following acute infection and identify risk factors for ocular disease to inform public health interventions for patients and the international community. The work responds to escalating mpox cases declared a public health emergency of international concern in 2024, with recent emergence in the United States, United Kingdom, Canada, India, and Thailand. The period of performance extends from August 1, 2026 through April 30, 2031. Work is performed in Omaha, Nebraska. The assistance type is a project grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $22.5k | 8/25/26 | ||
| Not listed | $29.2k | 8/13/26 | ||
| Not listed | $593.2k | 8/4/26 |