Project Grant R01EY035499

Award Date 9/30/24
Completion Date 8/31/28
Dollars Obligated $974K
Federal Grant Program
93.867
Assistance Type
Project Grant
Place of Performance
Michigan, USA
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  1. Perform untargeted metabolomics analysis on vitreous samples from patients with culture-positive bacterial and fungal endophthalmitis to identify unique metabolic signatures.

  2. Develop an artificial intelligence model to predict endophthalmitis etiology in culture-negative cases based on the vitreous metabolic profiles.

The research aims to discover potential biomarkers for diagnosing endophthalmitis and guiding appropriate antimicrobial therapy, with the ultimate goal of improving clinical outcomes for patients with this serious ocular infection.

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