This Project Grant award, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program, aims to investigate the impact of exposure to organophosphate flame retardants (OPFRs) on metabolic and brain aging. The total funding amount is $409,508, with the award period running from September 16, 2024 to August 31, 2026. The key products and services to be delivered under this grant include: Defining the extent to...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, provides $391,640 to Swarthmore College to conduct research on organophosphorus pesticide bioactivation and detoxification using a planarian invertebrate model. The overarching goal is to establish planarians as a cost-effective rapid screening model for studying the mechanisms of developmental neurotoxicity caused by chronic...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, is providing $728,408 to investigate genetic factors that influence susceptibility to pesticide-induced Parkinson's disease. The research aims to biologically validate novel candidate gene variants identified through prior epidemiological studies. The project involves two complementary research approaches: 1) evaluating the effects...
The National Institute of Environmental Health Sciences (NIEHS) awarded a $292,368 Project Grant under the Environmental Health (CFDA 93.113) federal grant program to the Regents of the University of Michigan. The grant, effective September 1, 2024 through March 31, 2026, will support research to "disentangle the drivers and dangers of toxic cyanobacteria biosynthetic heterogeneity in cyanobacterial harmful algal blooms (CyanoHABs)." The goal is to identify the effects of...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) federal grant program, will fund research to investigate the potential impacts of developmental exposure to pyrethroid pesticides on neurodevelopmental disorders (NDDs) using the prairie vole as an animal model. The $605,550 award, effective May 1, 2025 through February 28, 2030, will support the University of Toledo in conducting a comprehensive...
This federal Project Grant award, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research to define the neurotoxic and neurodevelopmental health risks of per- and polyfluoroalkyl substances (PFAS). The $546,350 award, effective January 13, 2025 through October 31, 2029, aims to characterize the mechanisms by which PFAS affect brain development and function. Key objectives include defining PFAS uptake...
The National Institutes of Health National Institute of Environmental Health Sciences awarded a $924,612 Project Grant to the California State University, East Bay Foundation, Inc. under the Environmental Health (CFDA 93.113) federal grant program. The grant will fund research from August 2022 to July 2025 to advance chemical risk assessment and predictive toxicology through the development, validation and integration of high-throughput mechanistic in vitro assays. Specifically, the grantee will...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA Program 93.853 "Extramural Research Programs in the Neurosciences and Neurological Disorders", provides $484,125.00 to Trustees of Dartmouth College to conduct research on "Mitochondrial Dynamics Underlying Oligodendrocyte Generation". The research aims to determine how disruptions and alterations in mitochondrial dynamics impact oligodendrocyte precursor cell fate...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $704,695 to The Roskamp Institute, Inc. to investigate the neurological effects of aerosolized red tide neurotoxins. The primary goals are to determine the dose-response relationship between aerosolized exposure to the neurotoxin brevetoxin and the development of neurological symptoms, as well as whether individuals with preexisting...
This Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) provides $497,069 to Beth Israel Deaconess Medical Center, Inc. (BIDMC) to conduct research on the mechanisms of cyanide-induced neurotoxicity and purine dysregulation. The research aims to elucidate the metabolite disturbances downstream of cyanide exposure, as well as develop new tools to investigate the effects of cyanide and other neurotoxicants on the nervous system. The...