Project Grant R01EB040161
- The National Institute of Biomedical Imaging and Bioengineering awarded $161,000 to the University of California, Davis on May 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop an affordable dynamic total-body positron emission tomography (TB PET) imaging system using sparse detector architectures. The research addresses cost barriers to TB PET adoption by reducing scintillator material and readout electronics...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of California, Davis $615,615 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop next-generation whole-body positron emission tomography (PET) scanners with enhanced spatial resolution and timing performance. The research aims to achieve sub-2 millimeter spatial resolution and approximately 8 cubic millimeter...
- The National Institute of Biomedical Imaging and Bioengineering awarded The Regents of the University of California, operating Lawrence Berkeley National Laboratory, $312,165 on June 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop Time-of-Flight Multi-Photon Emission Tomography (TOF-MPET) for direct imaging of therapeutic radionuclides in cancer treatment. The project addresses limitations in current imaging...
- The National Institute of Biomedical Imaging and Bioengineering awarded $447,728 to the University of California, Santa Barbara on August 5, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to design new bifunctional chelators that enable diagnostic imaging and targeted alpha particle therapy for cancer treatment. The project addresses two key limitations in alpha particle emitter-based radiopharmaceutical therapy: the...
- The National Institute of Biomedical Imaging and Bioengineering awarded the University of Southern California $291,496 on July 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop high-resolution three-dimensional electrical impedance mapping technology for identifying metabolically active atherosclerotic plaques. The project develops a balloon-deployable catheter platform integrating ultrathin, highly...
- The National Institute of General Medical Sciences awarded the University of Southern California $456,500 on September 1, 2026, through the Biomedical Research and Research Training program (CFDA 93.859) to decode and remotely reprogram cellular signaling networks. Work will extend through August 31, 2031, performed in Los Angeles, California. The recipient will develop multiplexed single-fluorophore biosensors to simultaneously visualize multiple signaling activities—including tyrosine kinase...
- The National Institute of General Medical Sciences awarded the University of Southern California $656,500 on April 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop technologies for studying and controlling cell patterning and differentiation in multicellular development, with a case study of multilayered arterial wall construction. The research will pursue two parallel tracks. The first develops technologies for three-dimensional differentiation...
- Federal Project Grant Award Summary The National Institute of Biomedical Imaging and Bioengineering awarded $630,000 to the University of California, Los Angeles under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) on September 1, 2025, with a completion date of August 31, 2028. This three-year project develops light-activated site-specific conjugation (LASIC) technology to advance the clinical translation of catheter-directed...
- Federal Project Grant Award Summary Vanderbilt University Medical Center received a $700,000 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded August 8, 2025, with completion by July 31, 2028. This award supports the development of novel radiosynthesis methods using direct [11C]CO2 methylation for production of carbon-11...
- The National Institute of General Medical Sciences awarded the University of California, Los Angeles $420,981 on March 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop engineered enzymatic catalysts for asymmetric hydrogen atom transfer reactions in synthetic chemistry. The research integrates organic chemistry, protein engineering, bioinorganic chemistry, and computational modeling to design and evolve biocatalysts that enable...
The National Institute of Biomedical Imaging and Bioengineering awarded the University of Southern California $663,498 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop a modular microscale platform for rapid 18F-radiopharmaceutical production via click chemistry and droplet radiochemistry. The project addresses barriers in positron emission tomography tracer development by creating a generalizable, scalable system that generates a universal 18F prosthetic group with a clickable handle, enabling rapid conjugation to small molecules or peptides under mild conditions. This approach eliminates the need for case-by-case radiochemistry optimization, minimizes precursor consumption, and enables parallel screening of candidate tracers. The platform leverages complementary expertise from University of Southern California and University of California, Los Angeles teams. Work is performed in Los Angeles, California, with a period of performance extending from September 1, 2026, through May 31, 2030. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $663.5k | 8/25/26 |