The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $519,210 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program to the Regents of the University of Michigan. The project aims to develop nanoparticle (NP) strategies to program circulating monocytes and neutrophils in order to disrupt the metastatic niche and enhance anti-tumor immune responses in triple-negative breast cancer. Specific...
This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the CFDA 93.286 "Discovery and Applied Research for Technological Innovations to Improve Human Health" program, aims to develop a highly sensitive magnetic levitation (MagLev) system to detect heterogeneity in protein corona (PC) composition on the surface of nanoparticles. The $370,503 award, effective from May 1, 2024 to March 31, 2026, will support research to...
The Trustees of the Colorado School of Mines received a three-year, $418,826 Project Grant from the National Cancer Institute, a division of the Department of Health and Human Services. The grant falls under the Cancer Detection and Diagnosis Research program (CFDA 93.394), which aims to improve cancer screening, early detection, and diagnostic techniques.
Under this award, the Colorado School of Mines will develop novel porous biomaterials containing immobilized metal catalysts and enzymes...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $650,503 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286) program to Brigham & Women's Hospital Inc. The project aims to develop a robot-assisted catheter placement system with a novel shape-sensing stylet to facilitate adaptive image-guided pelvic brachytherapy for the treatment of gynecologic malignancies. The system will combine a...
This National Science Foundation Project Grant of $605,170 will fund research into the biocompatibility of nanoparticles implanted intradermally as minimally invasive medical devices. Awarded on September 1, 2023 under the Engineering program (CFDA 47.041), the five-year project will be performed by the University of Colorado Boulder.
The grantee will create a library of nanoparticles varying in size, composition, density and stiffness for implantation in murine dermal tissue....
The National Institute of General Medical Sciences (NIGMS) awarded The Johns Hopkins University a $235,586 Project Grant (CFDA 93.859 Biomedical Research and Research Training) on June 3, 2024 to develop a genetically encoded magnetometer (GEM) capable of mapping heterogeneous intracellular magnetic fields at subcellular resolution without using harmful microwave radiation. The goal is to enable mechanistic studies of transcranial magnetic stimulation and magnetotherapy, as well as evaluate...
This federal Project Grant award from the National Cancer Institute's Cancer Detection and Diagnosis Research program (CFDA 93.394) provides $703,540 to Brigham & Women's Hospital to develop and optimize implantable microdevices for predicting patient response to cancer treatments. The key objectives are:
Validate the performance of the implantable microdevice technology to predict clinical response to immunotherapy and chemotherapy in head and neck cancer patients. This data will...
This National Science Foundation (NSF) Project Grant award of $275,000 to North Carolina State University (NC State) aims to study the feasibility of using sound waves to remotely control and propel microrobots through blood vessels. The goal is to develop microrobots capable of delivering drugs and providing wireless electrical stimulation to the nervous system, without requiring invasive surgery. The research plan includes three key objectives:
Investigating acoustic mechanisms to enable...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $275,773 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to Dropletpharm Inc., a for-profit company. The grant supports Dropletpharm's development of microfluidic technologies to enable low-cost and distributed manufacturing of radiopharmaceuticals for clinical and research applications.
Specifically, the project aims to expand...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the Department of Health and Human Services, aims to develop a laser-guided system for delivering high local doses of chemotherapy to the surgical cavity after tumor resection. The $374,095 award to Oncoblaze LLC, a for-profit organization, will fund the development of an infrared laser-based device that can trigger the release of chemotherapy from thermosensitive liposomal...