Project Grant R01EB037034
- Federal Grant Award Summary Texas A&M Engineering Experiment Station received a $395,695 Project Grant award dated August 1, 2025, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), administered by the National Institute of Biomedical Imaging and Bioengineering (NIBIB). The four-year project, extending through July 31, 2029, will develop novel multi-modal ultrasound imaging methods designed to serve as predictive markers...
- Federal Grant Award Summary Texas A&M Engineering Experiment Station received a $421,625 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), awarded July 1, 2025, with completion targeted for June 30, 2027. The project will develop advanced tumor microenvironment chips (TME-chips) incorporating perfusable blood and lymphatic capillary networks to model oral squamous cell carcinoma...
- Federal Project Grant Award Summary The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded the University of Texas at Arlington a $711,976 Project Grant (CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research) effective May 15, 2026, with completion targeted for April 30, 2031. This research initiative addresses the critical clinical need for improved diagnostic imaging of orthopedic implant infections (OII) caused by both gram-positive and...
- Federal Project Grant Award Summary Texas A&M Engineering Experiment Station is developing 3D-integrated micro-photometer chips for advanced neural recording applications under a $325,000 Project Grant awarded by the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041 - Engineering program). The project, initiated August 1, 2025 and extending through July 31, 2028, will produce miniaturized optoelectronic probes that integrate...
- Federal Grant Award Summary Texas A&M University received a $297,685 Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation (Engineering program, CFDA 47.041) beginning October 1, 2025 and concluding May 31, 2027. This collaborative research project investigates the mechanical properties and optimal design of biomimetic torene plates and shells—concentric shell structures with torus-shaped perforations inspired by the nuclear...
- Federal Project Grant Award Summary The University of Pennsylvania received a $646,506 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective September 5, 2025, through June 30, 2030. This award supports the development of dual-action nanoparticle-loaded microparticles designed to address osteoarthritis (OA) treatment through an innovative...
- Federal Project Grant Award Summary Texas A&M Engineering Experiment Station received a $300,000 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective September 1, 2025 through August 31, 2029. This award funds the development of a synthetic biology-based therapeutic delivery system that programs a probiotic bacterial strain (E. coli Nissle 1917) with multi-input...
- Federal Grant Award Summary The National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded $422,247 on September 15, 2025, to Lawrence Technological University under the Engineering program (CFDA 47.041) for a collaborative research project examining nanomaterial-cell interactions. This project grant, scheduled for completion by December 31, 2026, will deliver research findings on how nanoscale-structured surfaces influence cellular...
- Federal Project Grant Award Summary Penderia Technologies Inc. received a $306,722 project grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective September 19, 2025, with completion targeted for August 31, 2026. The award funds the development and characterization of an innovative distal femoral fracture (DFF) fixation plate incorporating an implantable,...
- Federal Grant Award Summary The University of Connecticut received a $400,000 Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041), effective October 1, 2025 through September 30, 2028. The project delivers research and development of immunomodulating cartilage tissue constructs designed to function in both terrestrial and space environments. The primary deliverables include engineered...
Texas A&M Engineering Experiment Station received a $483,246 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop two-dimensional nanosilicate biomaterials for cartilage regeneration and osteoarthritis treatment. The research, which commenced June 1, 2026 and extends through February 28, 2030, focuses on advancing a patented nanosilicate technology platform designed to deliver transcription factors that stimulate cartilage-specific matrix synthesis and facilitate in situ repair of articular cartilage defects. The project addresses a significant clinical need, as osteoarthritis currently affects over 27 million Americans with no disease-modifying treatments available. The deliverables comprise two primary research aims: (1) elucidation of molecular mechanisms underlying nanosilicate-induced chondro-inductivity in rodent osteoarthritis models, including optimization of intra-articular retention and cartilage regeneration stimulation; and (2) design, optimization, and validation of SOX9-loaded nanosilicates for healing critical-sized articular cartilage defects in large animal (swine) knee joint models. Key technical milestones include identification of the most effective nanosilicate formulation meeting desired in vitro properties and demonstration of efficacy in preclinical large animal studies. This technology development effort bridges fundamental bioengineering research with translational medicine objectives, positioning the nanosilicate platform for potential clinical translation in cartilage repair applications.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $483.2k | 5/12/26 |