Project Grant R01DK144492
- The federal Project Grant award of $237,750 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is supporting a research study to examine nephrology practices' participation decisions and care model reforms under Medicare's Kidney Care Choices payment models. The study, conducted by the Trustees of Indiana University (UEI: SHHBRBAPSM35), aims to better understand how smaller...
- This Project Grant award of $234,287 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to integrate clinical data and social determinants of health to map the social-environmental exposome and define its relationship to chronic kidney disease (CKD), particularly vitamin D status. The central hypothesis is that adverse social-environmental characteristics increase...
- This $128,286 Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research into the mechanisms of renal lipotoxicity and its contribution to the development of chronic kidney disease (CKD). The principal investigator will investigate the protective role of the FAF2 gene knockout in mitigating palmitate-induced lipotoxicity in...
- This $532,177 Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847), supports research to investigate a novel inflammatory pathway in diabetic kidney disease (DKD). The research aims to elucidate the role of the transcription modulator I-MFA in regulating inflammatory cytokine production by glomerular mesangial cells, a key contributor to DKD pathogenesis. The 4-year project at the University of North Texas Health Science Center will...
- This federal Project Grant award of $117,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports a systems biology research project conducted by the Regents of the University of Michigan. The key objectives are to: 1) Validate predicted transcription factor binding motifs related to the hypoxia-inducible factor 1-alpha (HIF1A) in areas of open chromatin using multiomics data, and 2)...
- This federal Project Grant award of $710,728 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research program) supports research by Oregon Health & Science University to define cell states in the kidney along the thick ascending limb, distal convoluted tubule, and connecting tubule. The research aims to characterize cell types in these regions, determine how potassium stress, diuretic drugs, water...
- This $2,833,514 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, titled "Renal Metabolism in AKI", will fund research to investigate changes in kidney metabolism in sepsis-associated acute kidney injury (AKI) and their impact on kidney tubule injury and recovery. The University of California, San Diego (UCSD) is the awardee...
- This federal Project Grant award, in the amount of $531,999.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award is supporting research focused on understanding the role of alternative splicing in the proximal tubules of the kidney and its relationship to the progression of diabetic kidney disease. The research will investigate how diabetes...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $659,182 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Rhode Island Hospital, a division of Lifespan Corporation. The funding will support research to elucidate the role and mechanism of histone deacetylase 6 (HDAC6) in cisplatin-induced kidney injury, fibrosis, and chronic kidney disease, and to identify HDAC6 inhibition as a novel approach for...
- This federal Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to investigate the molecular mechanisms driving the transition from acute kidney injury (AKI) to chronic kidney disease (CKD). The $1,491,303 award to The Washington University aims to characterize how the repression of the FOXM1-CCNF axis during tubular epithelial...
This $813,809.00 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will support a research project titled "Pathways Underlying Kidney Vulnerability in Outdoor Workers." The objective is to identify the contribution of heat stress and hyperthermia exposure to the risk of subclinical acute kidney injury (SAKI) and chronic kidney disease of non-traditional causes (CKDNT) among outdoor workers. The project will be conducted by the Trustees of Indiana University, with a performance period from Sep 15, 2025 to May 31, 2029. The research aims to improve understanding of the etiological pathways underlying the emerging public health issue of CKDNT associated with occupational heat stress exposure, particularly in geographic regions with seasonal temperature variations and workers at risk of traditional chronic kidney disease factors.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $813.8k | 9/15/25 |