The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $117,000 project grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to the Regents of the University of Michigan's Office of Research and Sponsored Projects Division, doing business as the University of Michigan. The grant, awarded on January 1, 2025, supports a systems biology approach to identify gene regulatory networks related to hypoxia inducible factor-1A (HIF1A) in the kidney cortex and medulla. The research aims to gain insights into how HIF1A target genes are differentially regulated in these regions, and to identify epigenetic alterations that may contribute to maladaptive repair after acute kidney injury. This project leverages multiome data from the Kidney Precision Medicine Project and will generate additional multiome data from kidney samples to achieve these research objectives. The anticipated completion date for the project is December 31, 2026.
Generated 3/4/25, 2:57 AM