Project Grant R03DK143117
- This $813,809.00 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will support a research project titled "Pathways Underlying Kidney Vulnerability in Outdoor Workers." The objective is to identify the contribution of heat stress and hyperthermia exposure to the risk of subclinical acute kidney injury (SAKI) and chronic kidney disease of non-traditional causes...
- The federal Project Grant award of $237,750 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is supporting a research study to examine nephrology practices' participation decisions and care model reforms under Medicare's Kidney Care Choices payment models. The study, conducted by the Trustees of Indiana University (UEI: SHHBRBAPSM35), aims to better understand how smaller...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $739,540 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Trustees of Columbia University in the City of New York for the development and validation of a third-generation polygenic score (GPS) for chronic kidney disease (CKD). The goal is to improve personalized risk prediction and accelerate the clinical implementation of polygenic prediction in...
- This $147,747 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant aims to elucidate the pathways from socioeconomic status (SES) to glycemic control and the onset of diabetes complications, with a focus on understanding how treatment intensification patterns mediate this relationship. The research plan includes: 1) summarizing...
- This federal Project Grant award of $117,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports a systems biology research project conducted by the Regents of the University of Michigan. The key objectives are to: 1) Validate predicted transcription factor binding motifs related to the hypoxia-inducible factor 1-alpha (HIF1A) in areas of open chromatin using multiomics data, and 2)...
- This $128,286 Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research into the mechanisms of renal lipotoxicity and its contribution to the development of chronic kidney disease (CKD). The principal investigator will investigate the protective role of the FAF2 gene knockout in mitigating palmitate-induced lipotoxicity in...
- This Project Grant award of $404,883 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop integrated spatial transcriptomics and proteomics technologies for studying kidney disease. The project, titled "Submicron-Resolution Integrated Spatial Transcriptomics and Proteomics for Studying Kidney Disease", will optimize a high-resolution spatial...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $231,270 to The Trustees of Columbia University in the City of New York to conduct large-scale rare variant analyses across major biobanks involving 1 million participants. The goal is to identify rare genetic variants and genes associated with chronic kidney disease (CKD), as well as develop and integrate...
- This $222,750 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) will support the development of a Social Determinants of Health (SDOH) index for assessing access to transplantation services for end-stage liver and kidney disease patients. The project aims to create a robust and widely accepted measure of SDOH relevant to transplantation, as the current literature has...
- This $223,176 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to characterize the role of apolipoprotein L1 (APOL1) copy number variations (CNVs) in kidney disease susceptibility among African Americans. The research, conducted by Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Boston, MA, aims to: 1) develop a computational...
This Project Grant award of $234,287 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to integrate clinical data and social determinants of health to map the social-environmental exposome and define its relationship to chronic kidney disease (CKD), particularly vitamin D status. The central hypothesis is that adverse social-environmental characteristics increase the risk of CKD comorbidities like vitamin D deficiency. The project, to be conducted by the Trustees of Indiana University in Indianapolis, will develop a secure dataset integrating electronic health records and geocoded census-level data on social determinants of health. This dataset will then be used to define social-environmental risk factors for vitamin D deficiency in children with CKD. The award has a period of performance from September 15, 2025 to August 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $234.3k | 9/15/25 |