Project Grant R01DK143448
- This Project Grant award, totaling $502,233, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the Regents of the University of Michigan to investigate neuron populations in the nucleus of the solitary tract (NTS) that mediate the aversive and non-aversive suppression of food intake. The research aims to further...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK, CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $410,000.00 to The University of Texas Southwestern Medical Center to study the effects of glucagon-like peptide 1 (GLP-1) receptor agonists and brain-derived GLP-1 on the activity of neuropeptide Y/agouti-related peptide (NPY/AGRP) neurons and their impact on metabolism. The research aims to define the...
- This Project Grant award of $666,229 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research on the role of the neuropeptide neurotensin (NTS) in the lateral nucleus accumbens (NACLat) to ventral tegmental area (VTA) pathway and its impact on hedonic feeding behavior. The project aims to study how NTS signaling in this neural pathway modulates reward-related feeding in mice, both on...
- This $769,097 Project Grant was awarded on September 5, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research conducted by the Pennington Biomedical Research Center in Baton Rouge, Louisiana to investigate a novel brain-to-pancreatic islet neural circuit that regulates glucose homeostasis. The research aims to establish the physiological...
- This Project Grant award, totaling $123,908, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The funding supports research at Baylor College of Medicine to investigate the role of the ANO4 calcium-activated chloride channel in the area postrema (AP) region of the brain, and its potential involvement in the orexigenic (appetite-stimulating) effects of the...
- This $2,560,698 federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to investigate the mechanisms by which animals learn about the nutrient content of foods and the neural pathways involved, with a particular focus on the lateralization of dopamine release in the brain. The research aims to reveal how...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $120,792 to the University of Alabama at Birmingham to conduct research assessing the mechanistic relationships between central amygdala neuron activity and glucagon-like peptide-1 receptor agonism. The project aims to pursue a functional analysis of GLP-1 receptors in the control of...
- This federal Project Grant award in the amount of $427,000 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to President & Trustees of Williams College. The award is funding a research project to study the role of the parasubthalamic nucleus (PSTN) in regulating feeding behavior and appetite suppression. The key objectives are to determine the afferent...
- This $802,363 federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will fund a research study at Emory University from September 2025 to June 2030 to develop models for predicting the benefits of GLP-1 receptor agonist (GLP-1RA) treatments in preventing obesity-related cardiometabolic diseases. The study aims to use clinical...
- This Project Grant award of $249,000.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) to New York University aims to improve understanding of how hunger and satiety neurons regulate the activity of downstream neurons in the hypothalamus. Specifically, the research will use novel molecular and optical tools to measure and manipulate cyclic AMP (cAMP) signaling in paraventricular hypothalamic neurons that express melanocortin-4 receptors (PVHMC4R), which...
This Project Grant award, valued at $747,133.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research by the Monell Chemical Senses Center to behaviorally, physiologically, anatomically, and molecularly characterize a population of neurons in the nucleus tractus solitarius (NTS) that express glucagon-like peptide-1 receptors (GLP1R) and project to the paraventricular hypothalamus (PVH). This research aims to determine the role of these NTSGLP1RPVH neurons in mediating the satiety and weight loss effects of GLP1-based obesity drugs like semaglutide, as well as map the neural circuits for non-aversive satiety. The project will run from September 2025 through May 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $747.1k | 9/5/25 |