Project Grant R01DK142071
- This Project Grant award of $356,032 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) supports the development of a novel bladder catheterization device. The project aims to create an innovative method for bladder drainage that addresses the significant morbidity and inconvenience associated with current catheterization approaches. Over 1 million Americans, including those with neurogenic bladder conditions, require catheter use for bladder drainage. The...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $708,138 to support the development of a biomechanocompatible small molecule-releasing scaffold for bladder augmentation. The goal is to create an alternative to conventional surgical approaches that use detubularized bowel tissue, which can have significant complications. The...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $176,201 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of California, Irvine. The grant, with an award date of July 15, 2025 and an ultimate completion date of March 31, 2030, will fund research to investigate the molecular changes in aging female urethral striated muscle and develop potential treatments for urethral dysfunction,...
- This Project Grant award of $177,350 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to advance sacral neuromodulation (SNM) treatment for overactive bladder (OAB) through the development of objective analytics and prediction methods. The project seeks to establish non-invasive functional near-infrared spectroscopy (fNIRS) techniques to detect real-time neural responses to acute SNM...
- This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $294,886 to Thormed Innovation LLC to develop a wearable, wireless ultrasound bladder monitoring system. The goal is to create a reusable, non-invasive device that can accurately measure urine output, reducing the need for invasive urinary catheters which are...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $862,002 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The Medical College of Wisconsin, Inc. The grant, awarded on March 1, 2025 with a completion date of February 28, 2030, will support an in-depth investigation of mechanisms for enhancing the motor function of fecal continence muscles to improve fecal incontinence in patients. The research aims...
- This Project Grant award, valued at $206,132 and provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), aims to develop a wireless, battery-free bioelectronic implant for closed-loop neuromodulation to treat detrusor sphincter dyssynergia (DSD) in individuals with spinal cord injury. The University of Houston System, the awardee, will fabricate and...
- This National Science Foundation (NSF) Cooperative Agreement under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) provides $975,713 in funding to Altyx Surgical, Inc. to develop and validate a novel, minimally invasive, mesh-free surgical device for treating stress urinary incontinence in women. The 2-year project aims to advance the surgical procedure and system from the prior Phase I proof-of-concept work, through activities including design optimization, testing, and...
- This federal Project Grant award of $432,625 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The purpose of the grant is to create a dataset measuring urological function in 8 different rat strains at various life stages. This dataset, combined with previous data, will help researchers understand how urological function differs across rat strains and guide...
- This federal Project Grant award of $690,451 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research on the role of bladder fibroblasts in regulating bladder function. The University of Pittsburgh will conduct studies to investigate the contractile properties of suburothelial fibroblasts and their contribution to the formation of bladder rugae, as well as the involvement of...
This Project Grant award of $1,429,924 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) is supporting the development of a novel, shape-changing sling for the treatment of stress urinary incontinence (SUI) in women. The goal is to create a minimally-invasive sling that can both support the urethra to achieve continence and be activated to reduce pressure on the urethra to enable complete voiding. The project is being conducted by the Texas A&M Engineering Experiment Station (Tees) and involves the fabrication and characterization of magnetically responsive elastomer slings with controlled mechanical properties and shape-changing capabilities. The award has a period of performance from September 18, 2025 to September 17, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.4m | 9/16/25 |