The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $299,999 Project Grant (CFDA 93.847) to Hibar Microsciences, LLC to develop a prototype for CLEAR, a novel hemodialysis cartridge designed to improve the clearance of protein-bound uremic toxins (PBUTs) from the blood of patients with end-stage renal disease. The key objectives are to: 1) Develop a method for immobilizing lipocalin proteins onto dialysis membrane matrices to enhance PBUT removal; 2) Create and...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $704,672 to Flowpoint Medical Inc. to develop an implantable self-sealing needle guide system to improve vascular access and safety for hemodialysis patients. The award will fund the refinement of the device's manufacturability and operational parameters, as well as a large animal...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $350,000 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Katharos, Inc., a for-profit woman-owned business based in Denver, Colorado. The goal of this 1-year project is to develop and evaluate a novel extracorporeal device called the "PhosFilter" that can enhance phosphate removal from the blood of patients undergoing hemodialysis for...
This $2,252,419 Cooperative Agreement award, funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), supports the development of an innovative vascular conduit device for dialysis vascular access. The award brings together industry and academic partners to create the "Functional Integrated Electrospun (FINE)" device, which comprises an inner...
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is focused on developing novel bioengineered regenerative medicine solutions based on vasculogenic regenerative medicine technology. The $543,826 award, granted on December 10, 2024, aims to investigate the mechanisms underlying in vivo vasculogenic reprogramming, specifically examining...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $298,371 to Anova Biomedical, Inc. to develop a new class of biodegradable and elastic vascular grafts for hemodialysis. The funding will be used to refine manufacturing techniques for these grafts, which are designed to closely resemble the mechanical properties of native vasculature and slowly remodel into...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $499,890 Project Grant (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) to Pavaj Vascular Corporation to develop a novel therapy to prevent arteriovenous fistula (AVF) venous stenosis, a common complication in end-stage kidney disease patients requiring hemodialysis. The funding will support two main goals: 1) evaluating the stability and biocompatibility of a nanoparticle-based...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $1,583,229 Project Grant to Boston Medical Center Corporation to evaluate the use of intravascular ultrasound (IVUS) imaging for diagnosing and managing arteriovenous (AV) access dysfunction in end-stage kidney disease patients on hemodialysis. The 5-year grant project will compare the accuracy of IVUS versus...
This Project Grant award of $200,000.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research to investigate the role of oxidative stress and the transcription factor Nrf2 in modulating the phenotype of vascular smooth muscle cells (VSMCs) and improving arteriovenous fistula (AVF) maturation. The research, to be conducted at the University of North...
This Project Grant award of $550,000 from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program will fund the development of a catheter monitoring system to reduce peritoneal dialysis (PD) infections. The project, led by The Johns Hopkins University, aims to develop a medical device that enables real-time, continuous, and quantitative monitoring of biomarkers relevant to PD-associated infections. This will involve optimizing the optical and flow...