Project Grant R01DE034438
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $582,000 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the University of Rochester. The grant, awarded on May 1, 2025, will support research aimed at understanding the mechanisms underlying peri-implantitis, an inflammatory condition affecting dental implants. The research will utilize a rat model of peri-implantitis to investigate the role of epigenetic factors, such as the...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded Rytek Medical Inc. a $220,000 Project Grant on August 1, 2025. The grant supports research to evaluate CT/X-ray imaging-correlated impedance-based metrics for predicting surgical osseointegration and injury prevention in dental implant procedures. The project aims to develop innovative diagnostic technologies, such as an impedance-based...
- This $164,255 federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, aims to develop innovative methacrylate-based dental materials that can inhibit the formation of microbial biofilms to prevent secondary caries. The key objectives are to: (1) synthesize a new 2-aminoimidazole derivative, H10, and generate a methacrylate-based antimicrobial agent containing covalently conjugated...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $421,800 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to Midwestern University. The purpose of this 3-year grant, with a start date of September 7, 2023, is to develop hybrid hydrogel-based dental adhesives that are less vulnerable to hydrolytic degradation compared to current methacrylate-based alternatives. The goal is to create a truly biomimetic dental adhesive that can not only...
- The National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), awarded a $273,009 Project Grant to Virginia Commonwealth University (VCU) to characterize a conserved streptococcal membrane protein affecting manganese utilization. The project aims to determine the crystal structure and functional role of this membrane protein, hypothesized to be an acyltransferase that incorporates polyunsaturated fatty acids...
- The $296,171 Project Grant awarded on August 8, 2025 by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to design and evaluate an impedance-based bone assessment technology for characterizing trabecular bone microarchitecture. This technology is intended to address the limitations of current imaging techniques, like cone beam CT, in accurately quantifying bone quality, particularly in the trabecular...
- This Project Grant award of $441,247.00, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), supports the development of a clinically-calibrated accelerated fatigue test for predicting the clinical performance of dental restorative materials. The project aims to create a Medical Device Development Tool (MDDT) in the form of an accelerated fatigue test that can explicitly predict the...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $685,594 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to The Pennsylvania State University (Penn State) to support research on leveraging microsurgery and bioprinting to enable rapidly vascularized tissue engineering for craniomaxillofacial (CMF) injury reconstruction. The project aims to advance a novel microsurgical "vascular micropuncture" technique to enhance the...
- This Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) provides $249,999 to The Trustees of the University of Pennsylvania for the development of a smart dental implant system. The award will support research and educational activities from September 2022 through August 2025. Specifically, the grantee will build a strategy to prevent peri-implant disease through enhancing soft tissue immunity near dental implants. They will develop an ambulatory care platform...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $673,091 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program to the University of Pittsburgh. The grant, which runs from August 14, 2025 to May 31, 2028, aims to advance the genomics knowledge base for oral diseases, focusing on dental caries and periodontitis. Key activities include performing the largest genome-wide association scans of these conditions, developing...
This $27,030 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, supports research to understand how biofilm formation and adhesion is affected by 3D-printed titanium surfaces used in dental implants. The key objectives are to develop experimental tools for measuring structural, deformation, and diffusive properties of single and multi-species oral biofilms on 3D-printed titanium materials. This research aims to provide insights into adverse biofilm configurations that resist deformation and have high adhesion, which can hinder the effectiveness of dental implants. The award period runs from August 1, 2025 to July 31, 2030, and the work is being conducted by the University of Kentucky Research Foundation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $27.0k | 7/25/25 |