This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under CFDA Program 93.173 "Research Related to Deafness and Communication Disorders", provides $1,403,696.00 to the University of Southern California (USC) to conduct research on using optical coherence tomography (OCT) imaging to visualize the fluid compartments of the human inner ear. The key goals of the project are to: 1) characterize the normal endolymph-to-perilymph ratio in control subjects with normal cochlear function, 2) compare the endolymph-to-perilymph ratio in subjects with Meniere's disease and vestibular schwannoma, and 3) validate the use of OCT for human inner ear imaging and support its use as an outcome measure for clinical trials of new treatments for Meniere's disease. This 5-year project, starting on December 1, 2024, aims to improve understanding of the underlying pathophysiology of sudden sensorineural hearing loss and related inner ear disorders.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $0 | 5/2/25 | ||
| Not listed | $701.8k | 11/25/24 | ||
| Not listed | $701.8k | 11/25/24 |