Project Grant R01DC022670

Award Date 5/2/25
Completion Date 4/30/30
Dollars Obligated $611K
Federal Grant Program
93.173
Assistance Type
Project Grant
Place of Performance
Pennsylvania, USA
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The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $610,725 Project Grant (CFDA 93.173 - Research Related to Deafness and Communication Disorders) to the University of Pittsburgh to conduct research on physiological mechanisms contributing to challenges faced by individuals with sensorineural hearing loss in understanding speech, especially in noisy environments.

The research program aims to characterize the effects of distorted cochlear tonotopicity and compensatory changes in neural excitation-inhibition balance on the neural coding and perception of speech-in-noise. Researchers will use psychophysical, EEG, and pupillometry methods to measure these suprathreshold deficits in a cohort of hearing loss patients and develop personalized profiles to predict speech understanding and listening effort with hearing aids. The findings are expected to broadly advance the field's understanding of the complex physiological effects of cochlear injury and central plasticity on the challenges faced by individuals with sensorineural hearing loss.

Generated 5/13/25, 5:26 AM