Project Grant R01DA067195
- The National Institute on Drug Abuse awarded Rutgers The State University of New Jersey, School of Nursing, $722,948 on September 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a randomized controlled trial examining the effects of tailored education about low-nicotine cigarettes on adult smokers' beliefs and behaviors. The research addresses a public health gap: U.S. adults conflate the addictive properties of nicotine with the health harms of tobacco...
- The National Institute on Drug Abuse awarded the University of Pittsburgh $700,254 on June 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to examine how combined nicotine and opioid exposure alters the prefrontal cortex in opioid use disorder. The research addresses the gap between current OUD treatments and patient outcomes, particularly the role of nicotine dependence as a confounding factor. Between 80–90 percent of individuals with OUD smoke, yet smoking...
- The National Institute on Drug Abuse awarded Virginia Commonwealth University $1,182,810 under the Drug Use and Addiction Research Programs (CFDA 93.279) on July 15, 2026, to identify and characterize non-nicotine compounds in electronic nicotine delivery systems that drive abuse liability through functional activity at nicotinic acetylcholine receptor subtypes. The award funds high-throughput screening methods to comprehensively identify pharmacologically active non-nicotine constituents in...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded $431,643 under its Drug Use and Addiction Research Programs (CFDA 93.279) to The Research Foundation for the State University of New York (SUNY at Binghamton) on August 1, 2025, for a two-year project concluding July 31, 2027. This Project Grant funds the development and pilot testing of a telehealth-delivered, pain-targeted motivational smoking intervention designed for smokers with chronic pain who are not ready to...
- The National Institute on Drug Abuse awarded Virginia Commonwealth University $657,471 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to assess the abuse liability of 6-methyl nicotine, a synthetic nicotine analog used in electronic nicotine delivery systems. The research addresses the regulatory gap created by manufacturers using synthetic nicotine analogs to circumvent nicotine-focused regulations, particularly as ENDS use remains the most prevalent form...
- The National Institute on Drug Abuse awarded the Research Foundation For Mental Hygiene, Inc. (operating through its New York State Psychiatric Institute division) $195,804 on August 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279). The award funds a five-year research project examining how cannabis influences nicotine use among young and emerging adults (ages 18–35) who use electronic nicotine delivery systems. The study integrates human laboratory methods with...
- The National Institute on Drug Abuse awarded Yale University $190,580 on March 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop and pilot a multiple health behavior change intervention targeting concurrent weight loss and smoking cessation among pre-bariatric surgery patients. The award funds a pilot randomized controlled trial enrolling 64 adult pre-surgical patients with severe obesity who smoke. The intervention arm (32 participants) will complete a 4-month...
- The National Institute on Drug Abuse awarded The Medical University of South Carolina $249,000 on June 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate how social-contextual stressors affect smoking cessation and relapse among socioeconomically disadvantaged young adults who smoke. The recipient will conduct mixed-methods research combining qualitative interviews and ecological momentary assessment (EMA) to examine the lived experiences of...
- The National Institute on Drug Abuse awarded Virginia Commonwealth University $149,766 on August 17, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct basic research on LYNX1 allosteric modulation of α3β4-nicotinic receptors and its relevance to nicotine use disorder. The fellowship project addresses two unresolved questions in nicotine addiction neurobiology. The recipient will conduct saturation and competition binding assays on heterologously expressed...
- The National Institute on Drug Abuse awarded Rutgers The State University of New Jersey (doing business as RBHS-School of Nursing) $2,107,844 on September 15, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a longitudinal mixed-methods study of nicotine pouch adoption and use patterns among U.S. adults. The research combines a nationally representative longitudinal survey with qualitative interviews to examine who uses nicotine pouches, reasons for adoption,...
The National Institute on Drug Abuse awarded Duke University $722,472 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a randomized, double-blinded study examining very low nicotine content cigarettes as a smoking cessation intervention for individuals with chronic back pain. The research addresses high comorbidity between tobacco smoking and chronic pain, where nicotine's mild anti-nociceptive effects create powerful negative reinforcement and chronic exposure produces hyperalgesia exacerbated by withdrawal. Preliminary pilot data from 35 participants showed that four weeks of very low nicotine content cigarettes led to significant decreases in back pain intensity correlated with reduced dependence, while participants experiencing pain reduction were more likely to achieve abstinence three months later. The full study will assign smokers with non-cancer chronic back pain interested in quitting to smoke either very low nicotine content or normal nicotine content cigarettes for four weeks, then initiate a supported quit attempt with counseling. Participants will complete remote daily assessments of cigarette use, withdrawal, and pain intensity and interference, plus weekly assessments of toxicant exposure and dependence. The study will apply machine learning techniques to identify predictors of treatment response and determine which individuals are most likely to benefit. Work is performed in Durham, North Carolina. The period of performance runs from September 1, 2026, through June 30, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $722.5k | 8/24/26 |