Project Grant R01DA066062
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded McLean Hospital Corporation a Project Grant totaling $194,206 under the Drug Use and Addiction Research Programs (CFDA 93.279) for the period June 1, 2026 through May 31, 2031. This five-year research initiative aims to identify individual clinical and environmental predictors of buprenorphine treatment response in patients with opioid use disorder (OUD). The project will harmonize data from five existing clinical...
- Federal Grant Award Summary This $716,669 Project Grant, awarded June 1, 2026, by the National Institute on Drug Abuse through the Drug Use and Addiction Research Programs (CFDA 93.279), supports a longitudinal research study examining metacognition circuit impairments in opioid use disorder (OUD). The research will deliver foundational neuroscience and clinical evidence regarding how second-order cognitive deficits—specifically metacognitive underconfidence—correlate with anterior prefrontal...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Massachusetts Medical School a $1.74 million Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning July 15, 2025, with completion targeted for March 31, 2030. This award supports research focused on the discovery and functional characterization of long non-coding RNAs (lncRNAs) in opioid use disorder (OUD) within the context of HIV at single-cell resolution. The...
- Federal Grant Award Summary McLean Hospital Corporation received a $451,000 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a biometrics-based platform for predicting opioid relapse. The award, effective May 15, 2026, through April 30, 2028, supports an R21 exploratory development project that applies machine learning (ML) algorithms to integrate physiological, behavioral, and subjective mood state data...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Massachusetts Medical School a $1.62M Project Grant on August 1, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the role of striatal molecular rhythms in sleep disruption and opioid use disorder (OUD). The research will be conducted through April 30, 2030, and addresses the critical gap in understanding how molecular rhythm disruptions in the brain's reward and...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $777,565 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) under the Drug Use and Addiction Research Programs (CFDA 93.279) on May 15, 2026, with completion targeted for February 28, 2031. This project delivers quantitative evidence to inform personalized medication for opioid use disorder (MOUD) treatment protocols during the critical first 24 weeks of...
- Federal Project Grant Award Summary New York University School of Medicine received a $2.09 million Project Grant award dated July 1, 2025, from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to characterize complex opioid use disorder (OUD) care trajectories and outcomes following acute service utilization. The grant supports a population-based data linkage study examining patients who experienced opioid-related hospital encounters...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded University of Colorado-Denver a $709,085 Project Grant effective April 1, 2026, through January 31, 2031, under the Drug Use and Addiction Research Programs (CFDA 93.279). This implementation trial will develop and test a facilitation intervention to increase in-hospital opioid treatment program (OTP) intake completion among hospitalized patients with opioid use disorder (OUD). The study employs a novel...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $197,640 Project Grant to Massachusetts General Hospital (MGH), effective March 1, 2026 through February 28, 2030, under the Drug Use and Addiction Research Programs (CFDA 93.279). This research project investigates the clinical impact and cost-effectiveness of integrating infectious disease (ID) care into rapid-access substance use bridge clinics. The principal investigator, an infectious disease physician and...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Johns Hopkins University a $1.54 million Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) on August 1, 2025, with a completion date of April 30, 2030. The STRONG study (Informing Best Practices for Substance-Use Treatment with Real-World Evidence for People with Opioid Use Disorder and HIV) will comprehensively characterize opioid use disorder (OUD) treatment and HIV outcomes...
The National Institute on Drug Abuse (NIDA) awarded McLean Hospital a $736,811 Project Grant (CFDA 93.279: Drug Use and Addiction Research Programs) effective June 1, 2026, through March 31, 2031, to conduct a longitudinal cohort study characterizing the long-term course of opioid use disorder (OUD) in adults. The study will follow 550 individuals with OUD recruited from multiple sites across the United States, utilizing an innovative remote assessment methodology comprising monthly patient-reported outcomes supplemented by annual interviewer-administered assessments. This approach represents a significant methodological advancement over prior longitudinal studies by providing high-quality, temporally precise data rather than relying on retrospective recall over extended periods. The research will examine not only substance use outcomes but also broader recovery domains, including non-abstinent outcomes, to identify factors influencing long-term treatment trajectories and risk for sustained opioid use. This study directly addresses critical knowledge gaps resulting from the rapidly evolving treatment landscape for OUD, including the expansion of low-barrier buprenorphine access, FDA approval of extended-release injectable buprenorphine formulations, and the saturation of illicit drug supplies with fentanyl and other potent synthetic opioids. The research will employ rigorous longitudinal data analysis methods to advance understanding of recovery processes and treatment effectiveness within the current public health environment, supporting evidence-based refinement of treatment and policy initiatives.Federal Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $736.8k | 5/25/26 |