Project Grant R01DA063453
- The National Institute on Drug Abuse awarded New York University $411,187 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct basic research on trial-to-trial variability in neural circuits and its impact on neural computation and behavioral accuracy. The project integrates theoretical models, statistical methods, and experimental datasets to characterize noise in neural circuits using rodent navigation and nonhuman primate decision-making tasks. The...
- The National Institute on Drug Abuse awarded The Trustees of Princeton University $473,543 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop theoretical frameworks and computational methods for identifying mechanisms of cognitive computations from neural recordings and behavioral data. The award funds three research aims: formulating mathematical theory relating the dimensionality of neural population dynamics to single-cell selectivity patterns...
- The National Institute on Drug Abuse awarded the Regents of the University of Michigan $325,904 on March 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop real-time machine learning methods for constructing and perturbing stimulus-shaped neural manifolds. The project deliverables span three aims: developing real-time dimensionality reduction algorithms to construct neural manifolds shaped by external stimulus information; designing probabilistic models for...
- The National Institute on Drug Abuse awarded The University of Chicago a $1.010 million cooperative agreement on April 15, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate how social experiences during adolescence affect neurodevelopmental mechanisms regulating addiction susceptibility. The research integrates behavioral assays, computational tools, drug self-administration studies, and single-cell genomic analyses in rats across adolescence and adulthood....
- The National Institute on Drug Abuse awarded Northwestern University $722,218 on March 1, 2026, for research on the effects of developmental environment on dopamine circuit structure and function under the Drug Use and Addiction Research Programs (CFDA 93.279). The project runs through December 31, 2030, with place of performance in Chicago, Illinois. The research investigates how early life stress produces long-lasting impacts on dopamine circuit function and development into adulthood, using...
- The National Institute on Drug Abuse awarded the University of Illinois $726,413 under the Drug Use and Addiction Research Programs (CFDA 93.279) on August 1, 2026, for a Project Grant to examine neural and computational markers of reward processes as longitudinal risk markers of cannabis use escalation in young adults with anhedonia. The research investigates how acute laboratory administration of delta-9-tetrahydrocannabinol (D9-THC) versus placebo affects reward processing in individuals aged...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $1,080,885 to the University of Southern California (USC) from September 2024 to September 2027. The funding supports the development of novel neural network models that can capture the nonlinear dynamics of large-scale brain networks and their relationship to behavior. The models will have flexible inference capabilities, enabling real-time,...
- The National Institute on Drug Abuse awarded the Lieber Institute Inc. $1.855 million on March 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop three-dimensional cellular resolution spatio-molecular maps of the human nucleus accumbens across its anterior-posterior axis. The nucleus accumbens is a key node in the brain's reward circuitry, and perturbations in reward signaling are implicated in substance use disorders. The project extends prior spatial...
- The National Institute on Drug Abuse awarded New York University a cooperative agreement valued at $1,240,576 on March 15, 2026, to develop and validate an integrated system for life-long, high-resolution monitoring of mouse colony life to study neurobehavioral mechanisms of social behavior and familial structure. This award falls under the Drug Use and Addiction Research Programs (CFDA 93.279), which supports basic, clinical, translational, and implementation research to advance knowledge and...
- The National Institute on Drug Abuse awarded The University of Chicago $1,105,220 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct the Pathways to Improved Health and Housing Study, a hybrid type 2 implementation-effectiveness research study examining bundled interventions to improve HIV, substance use, and housing outcomes among individuals with criminal legal system involvement who use substances and are living with or vulnerable to HIV. The...
The National Institute on Drug Abuse awarded The University of Chicago $390,600 on September 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop coarse-graining theory, models, and methods that translate approaches to describing emergent collective behavior in neural systems into usable code for the broad neuroscience community. The project will produce data analysis code made available to neuroscience researchers for use on their own datasets. Three theorists will develop methods for finding and interpreting relevant modes of population activity in the brain, examining both instantaneous snapshots of activity and activity as it evolves over time. The approach will be validated across neural systems at different processing stages and scales—from salamanders to rodents to humans, from the retina to the cortex, from tens to thousands of cells—by verifying that the neural code can be read out with high fidelity after compression into a smaller subspace. The award supports basic research addressing the need for theoretical and computational approaches to guide exploration of emergent behavior in large neural populations, enabling conversion of high-volume neural recording data into actionable scientific insight. Performance occurs in Illinois with ultimate completion on June 30, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $390.6k | 9/1/26 |