Project Grant R01DA062848
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $197,640 Project Grant to Massachusetts General Hospital (MGH) under the Drug Use and Addiction Research Programs (CFDA 93.279) effective March 1, 2026 through February 28, 2030. This four-year research initiative will deliver clinical outcomes research and health economic analysis examining the integration of infectious disease (ID) care into rapid-access substance use disorder (SUD) bridge clinics. The...
- Federal Grant Award Summary The University of Massachusetts Medical School received a $1.17 million Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) awarded July 15, 2025, with a completion date of March 31, 2030. This award supports basic research focused on the discovery and functional characterization of long non-coding RNAs (lncRNAs) in opioid use disorder (OUD) within the context of HIV at single-cell resolution. The...
- Federal Project Grant Award Summary Massachusetts General Hospital (MGH), a Harvard Medical School-affiliated academic medical center, received a $330,000 Project Grant award from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) on March 15, 2026, for completion by February 29, 2028. The grant funds a machine learning-driven research initiative titled "Uncovering Patterns in the Evolving Drug Supply to Detect Emerging Overdose Trends...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Massachusetts Medical School a $825,383 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning August 1, 2025, with completion targeted for April 30, 2030. This research project investigates the role of striatal molecular rhythms in sleep disruption and opioid use disorder (OUD), addressing the critical public health challenge of high relapse rates among individuals...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Boston Children's Hospital a $489,500 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning June 1, 2025 and concluding May 31, 2027. This research initiative develops and validates remote oral fluid testing procedures to assess cannabis non-use as a key outcome measure in clinical trials targeting younger adults aged 18-30 years with cannabis use disorder (CUD). The project...
- Federal Project Grant Award Summary Boston University Medical Campus received a $109,076 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) with an award date of January 9, 2026 and completion date of July 31, 2029. The award funds basic research to elucidate the role of G Alpha Z (GAZ) protein in behavioral responses to opioids. The research will characterize GAZ expression and downstream signaling pathways in...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a $742,500 Project Grant (R34) to Massachusetts General Hospital on July 15, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279). This three-year pilot study, concluding June 30, 2028, will develop and test a peer recovery coaching intervention designed to promote tobacco abstinence in individuals with concurrent opioid use disorder and tobacco use disorder (MOUD-TUD). The project will adapt an...
- Federal Grant Award Summary Massachusetts General Hospital received a $3.29 million Project Grant from the National Human Genome Research Institute (NHGRI) under the Human Genome Research program (CFDA 93.172), awarded on September 17, 2025, with completion targeted for August 31, 2029. This award supports the development of computational and statistical methods to advance genome-wide association studies (GWAS) of disease course over time using longitudinal data from large biobanks such as the...
- Federal Project Grant Award Summary Baystate Medical Center, Inc. received a $905,970 Project Grant award from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning September 1, 2025, with completion targeted for August 31, 2026. The award supports the development and testing of Relational Health Enhanced Parenting Support (RHEP), a multilevel implementation strategy bundle designed to improve the delivery of evidence-based parenting...
- Federal Project Grant Award Summary The University of Massachusetts Medical School received a $1.50M Project Grant award from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning September 1, 2025, and concluding May 31, 2030. The grant funds the "Clinical Organization and Legal Agency Alliance Building" (COLAAB) Study, an implementation science initiative designed to increase access to Medications for Opioid Use Disorder...
Massachusetts General Hospital received a $769,268 Project Grant award from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279), effective March 1, 2026 through December 31, 2029. The award supports a comprehensive research study examining the ethical, clinical, and practical implications of genomic tests using polygenic risk scores (PRS) to estimate individual genetic risk for opioid use disorder (OUD) and other substance use disorders (SUD). The research addresses critical gaps in understanding how these novel genetic tests—including an FDA-approved test for OUD—should be integrated into clinical care while balancing pain management benefits against addiction risks and associated societal harms. The study's primary deliverables include empirical research examining key stakeholder perspectives (patients, clinicians, genetic counselors, and other relevant parties) on the reliability and appropriate clinical use of genetic risk tests for OUD and SUD. Research outputs will address critical questions regarding test ordering criteria, management of genetic risk information in medical records, data access and privacy protections, stigma-related barriers to adoption, and potential misuse scenarios. By generating evidence on the ethical and clinical implications of these emerging genetic technologies, the project aims to inform clinical decision-making and policy development for the responsible integration of genomic testing into substance use disorder prevention and treatment workflows.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $769.3k | 2/26/26 |