Project Grant R01DA061808
- The National Institute on Drug Abuse (NIDA) awarded a $109,076 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Illinois on January 25, 2026. The grant will fund a research project to examine the impact of ovarian hormone mechanisms on acute risk for problematic cannabis use in females, particularly during periods of hormonal fluctuation across the menstrual cycle. The project will leverage a novel computational modeling approach to analyze...
- This Project Grant award of $1,315,596.00 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to use animal models to understand how maternal exposure to electronic nicotine delivery system (ENDS) aerosols during pregnancy impacts addiction-related behaviors and neurocircuitry in offspring. The project will examine the effects of maternal inhalational exposure to commercial ENDS aerosols (fruit- and tobacco-flavored) on...
- This Project Grant award for $194,375.00 was provided by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports research to investigate sex-biased, region-specific regulation of dopamine release and clearance, with a focus on understanding the neural substrates linking steroid hormone signaling to synaptic dopamine availability. The research aims to elucidate the critical...
- The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $265,239 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of North Carolina at Chapel Hill (UNC-CH) to investigate the effects of vaping-induced oxidation on nicotine analogs in e-cigarettes. The project aims to evaluate the chemical composition of 6-methyl nicotine and nicotinamide vaping products before and after aerosolization, and assess...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, supports research under the Drug Use and Addiction Research Programs (CFDA 93.279) on the interplay between norepinephrine and dopamine circuits in the brain and their role in sex differences in reward and aversion. The $781,032 award, spanning August 2025 to April 2030, will map the anatomical and neurochemical distribution of norepinephrine projections from the locus...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), part of the Department of Health and Human Services' Drug Use and Addiction Research Programs (CFDA 93.279), provides $147,486 to the Icahn School of Medicine at Mount Sinai to investigate the combined impact of HIV infection and nicotine use on neuroinflammation. The research aims to elucidate the role of the NLRP3 inflammasome in driving CNS inflammation, blood-brain barrier disruption, and viral reactivation in...
- This $693,491 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a mixed methods study to advance the scientific understanding of nicotine pouch use among U.S. adults. The study will employ a nationally representative longitudinal survey integrated with qualitative interviews to investigate who is using nicotine pouches, their reasons for use, methods, frequency, and intensity of use, as well as...
- The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, has awarded a $718,374 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of Nebraska Medical Center (UNMC). The 5-year grant, effective September 1, 2025, will support research to uncover how the co-exposure of nicotine exacerbates the adverse effects of antiretroviral drugs on placental development in pregnant women living with HIV-1. The study aims to employ...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded a $654,500 Project Grant to the University of Tennessee Health Science Center in Tennessee. The grant, with a performance period from July 15, 2025 to March 31, 2030, will support research to investigate how social environment influences the hedonic value of nicotine and nicotine addiction. The project aims to study the role of the CACNA1C gene and the oxytocin receptor in...
- This federal Project Grant award of $623,650 was provided by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant is funding research at Oregon Health & Science University to investigate how adolescent social isolation and disruption of thyroid hormone signaling in the basolateral amygdala may contribute to substance use disorder vulnerability. The project aims to elucidate the...
This Project Grant award from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, supports research to understand the effects of endogenous and exogenous ovarian hormones on the use of electronic nicotine delivery systems (ENDS), particularly among young adults. The total award amount is $784,528 over a period from August 1, 2025 to April 30, 2030. The grant recipient is The Miriam Hospital, a division of Lifespan located in Providence, Rhode Island. The research aims to explore three key pathways linking ovarian hormones to nicotine use, including the impact of natural hormonal fluctuations during the menstrual cycle and the effects of synthetic estrogen from oral contraceptives on nicotine metabolism and use. This work falls under the Drug Use and Addiction Research Programs (CFDA 93.279) which supports scientific research to understand, prevent, and treat substance use disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $784.5k | 7/29/25 |