This Project Grant award of $320,000 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is funding the development of an innovative e-cigarette vaping treatment for nicotine addiction. The primary goal is to explore the feasibility of delivering the smoking cessation drug candidate cytisine through electronic vape administration (EVA) to stabilize dopamine release and reduce nicotine self-administration in a mouse model of...
The National Institute on Drug Abuse (NIDA) awarded a $141,203 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to Portland State University (PSU). The overarching goal of this 4-year project, beginning May 1, 2024, is to bridge significant knowledge gaps in understanding how specific chemical formulations and vaporizer designs exacerbate the formation of toxic emissions, particularly the deadly toxicant ketene, during cannabis vaping. The project will develop...
This Project Grant award of $1,508,782 from the National Institute on Drug Abuse (NIDA), under CFDA 93.279 Drug Use and Addiction Research Programs, will fund research to assess the impact of e-cigarette use on lung health in young adults. The primary award recipient, the University of Virginia, will use advanced imaging techniques, specifically 3D hyperpolarized xenon-129 MRI (HXMRI), to quantify changes in pulmonary gas exchange capacity within the lungs of e-cigarette users compared to...
This $187,500.00 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, will fund research at North Carolina Central University (NCCU) to assess the impact of vaping on lung health and susceptibility to pulmonary infections.
The key objectives of this project are to: 1) model the effects of e-cigarette exposure on human bronchial epithelial cells, 2) evaluate the impact of vaping on immune cell...
This National Institute on Drug Abuse (NIDA) project grant under the Drug Use and Addiction Research Programs (CFDA 93.279) will provide $241,500 in funding to Duke University from September 2024 to July 2027. The project aims to evaluate the effects of switching people who smoke and have opioid use disorder and chronic pain to very low nicotine content (VLNC) cigarettes. The research will use ecological momentary assessments to examine how VLNC cigarette use impacts the bidirectional...
This $549,555.45 Project Grant award from the National Institutes of Health (NIH) Office of the Director supports research under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077). The award will fund a cross-sectional study to investigate the relationship between electronic cigarette (e-cigarette) use and exposure to chemical constituents of concern (CCOC), such as metals and aldehydes, as well as the association with respiratory health outcomes...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $2,630,395 to The Johns Hopkins University to conduct laboratory studies investigating the impact of acute delta-9-tetrahydrocannabinol (THC) administration on the motivational, subjective, and physiological effects of combustible cigarettes and electronic cigarettes. The studies will use standardized nicotine products to determine how THC...
The National Institute on Drug Abuse (NIDA) awarded a $1,973,823 Project Grant (CFDA 93.279 - Drug Use and Addiction Research Programs) to the Medical University of South Carolina (MUSC) to evaluate a tobacco harm reduction strategy among clients enrolled in substance use disorder (SUD) treatment. The study will compare the efficacy of switching to electronic nicotine delivery systems (ENDS) versus using nicotine replacement therapy (NRT) to promote abstinence from cigarettes. The project...
This $622,957 federal Project Grant award, funded by the National Institutes of Health (NIH) under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077), will support research to investigate the chemical composition and behavioral effects of new tobacco products, including oral nicotine pouches (ONPs) and "non-menthol" cigarettes.
The key objectives of this 4-year award to Duke University are to: 1) analyze the chemical composition of ONPs...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $230,618 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Trustees of Indiana University, doing business as Indiana University Indianapolis (IU Indianapolis). The grant, awarded on January 8, 2025, supports research to investigate the mechanisms by which vaping the vitamin E acetate compound "α-tocopherol-acetate" (A-T-acetate) generates a novel toxic compound...