This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop efficient statistical methods for data fusion to improve the power and external validity of clinical trials for treating opioid use disorder. The $564,326 award, with a performance period from August 2024 to May 2029, will fund the development of new parametric and semiparametric estimators for average treatment effects,...
This federal Project Grant award for $4,319,168.00, awarded by the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs), supports research to investigate the functional connectivity mechanisms of opioid abstinence. The award was granted to Yale University and aims to address the significant public health challenge of opioid use disorder (OUD), which has reached epidemic levels in recent years. The research will examine the neurological underpinnings of OUD...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to generate evidence that can inform effective prevention and treatment strategies for adolescent drug overdose. With $431,750 in funding over a 2-year period from September 2024 to September 2026, the project will: Estimate the prevalence of nonfatal adolescent drug overdose and identify high-risk demographic and clinical subgroups, stratified by drug...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Federal Grant Program "Drug Use and Addiction Research Programs" (CFDA 93.279), provides $1,607,146 over 2 years to NDRI-USA Inc., a non-profit research organization based in New York. The funding will support the development of technology-based interventions to encourage drug checking, distribution of harm reduction supplies, and linkage to substance use services. The project aims to address the...
This $2,316,128 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to design and assess tailored harm reduction strategies to address the overdose crisis across six distinct jurisdictions. The project, titled "REVERSING OVERDOSE EPIDEMICS THROUGH SIMULATION, COLLABORATION, AND UNIFIED EFFORTS (RESCUE)," will collaborate with health departments and community partners to evaluate the effectiveness,...
This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports the development of novel econometric research methods to integrate real-world data and evidence (RWE) into inconclusive randomized controlled trials (RCTs) for opioid use disorder (OUD) treatments. The $2,542,500 award to Weill Medical College of Cornell University will fund a 3-year project to adapt existing econometric and...
This Project Grant award of $193,336 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to evaluate the impact of a pharmacist-integrated model of opioid use disorder (OUD) treatment on increasing naloxone co-prescribing in primary care settings. The key objectives are to: 1) describe federal, state, and clinic-level policies and current OUD interventions impacting naloxone co-prescribing at four primary care sites; 2)...
This federal Project Grant award of $459,045 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to modify the Opioid Use Disorder (OUD) Cascade of Care model to better reflect the changing landscape of real-world OUD treatment. The project will link data across healthcare and substance use treatment systems in Los Angeles County to construct a cross-system OUD care cascade, with the ultimate goal of reducing OUD-related...
This $715,238 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) is focused on conducting a large-scale genome-wide association study (GWAS) to elucidate the genetic basis of opioid-related traits and opioid use disorder (OUD). The key objectives are to: 1) Deploy a survey to 500,000 diverse participants from 23andMe to collect data on pre-addiction phenotypes (e.g., initial opioid use, subjective opioid response)...
This $157,684 federal Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) will fund a study to understand inequities in harm reduction services provided to persons with opioid use disorder in hospital settings. The project aims to develop and validate a natural language processing (NLP) system to identify patterns of harm reduction language and other relevant data in electronic health record (EHR) clinical notes....