Project Grant R01CA301509
- Federal Grant Award Summary The University of California, San Francisco received a $729,587 Project Grant award from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) on August 21, 2025, with completion targeted for July 31, 2030. This award supports the development and validation of a personalized, voxel-wise prediction model for brain metastases using multi-parametric magnetic resonance imaging. The research addresses a critical gap in radiotherapy...
- Federal Grant Award Summary The National Cancer Institute awarded a Project Grant of $149,394 to the University of California, Davis, effective August 1, 2025, through July 31, 2030, under the Cancer Detection and Diagnosis Research program (CFDA 93.394). This award supports targeted radiotheranostics research—the development and clinical translation of radiopharmaceuticals that combine diagnostic imaging and therapeutic capabilities for oncology applications. The project focuses on designing,...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded $185,760.00 to The Regents of the University of California, San Francisco under the Cancer Research Manpower program (CFDA 93.398) on July 7, 2025. This Project Grant funds research aimed at enhancing treatment outcomes for metastatic castration-resistant prostate cancer (MCRPC) through the development of novel tumor-targeted combination therapy. The primary research deliverable involves creating a single...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a $584,521 Project Grant on August 8, 2025, under the Cancer Treatment Research program (CFDA 93.395) to conduct a five-year research initiative (completion date: July 31, 2030) investigating subclonal determinants of radiation response in soft tissue sarcomas. The research will deliver three primary products: (1) identification and validation of epigenetic changes, including DNA...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $382,449 Project Grant to the University of California, Los Angeles under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on July 16, 2025, with completion targeted for June 30, 2027. This research project develops and validates advanced dual-nuclei magnetic resonance imaging (MRI) techniques to non-invasively differentiate between recurrent brain metastases (RBM) and radiation-induced necrosis (RN)...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a $730,398 Project Grant to Sloan-Kettering Institute for Cancer Research under the Cancer Treatment Research program (CFDA 93.395) effective April 1, 2026, through March 31, 2031. This research initiative focuses on understanding and overcoming treatment resistance in locally advanced rectal cancer (LARC) patients undergoing total neoadjuvant therapy (TNT)—a combined treatment regimen consisting of radiation therapy,...
- Federal Project Grant Award Summary The University of California, San Francisco (UCSF) received a $718,456 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded July 1, 2025, with a completion date of May 31, 2029. This four-year research initiative focuses on developing an artificial intelligence (AI) system capable of automated,...
- Federal Project Grant Award Summary The University of California, San Francisco received a $421,685 Project Grant from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) to investigate discovery methods for identifying functional immune niches within the tumor microenvironment (TME). Awarded on August 8, 2025, with a completion date of July 31, 2027, this research project will deliver scientific discoveries regarding the cellular and molecular mechanisms that...
- Grant Award Summary The National Cancer Institute (NCI) awarded The Leland Stanford Junior University a Project Grant totaling $593,557 on March 18, 2026, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to support research on novel magnetic resonance (MR) methods for monitoring and controlling BPM31510, an emerging lipophilic cancer therapeutic agent. The research initiative, spanning from March 2026 through February 2031, addresses a critical gap in cancer treatment...
- Federal Project Grant Award Summary The National Cancer Institute awarded a Project Grant of $677,787 to The Regents of the University of California, San Francisco on August 26, 2025, under the Cancer Treatment Research program (CFDA 93.395) to support a five-year research initiative extending through July 31, 2030. The project, titled "Aire-Expressing Macrophages as Novel Mediators of Tumor Immune Evasion," focuses on identifying and characterizing tolerogenic macrophage populations...
The National Cancer Institute (NCI) awarded $700,838 to the University of California, San Francisco under the Cancer Detection and Diagnosis Research program (CFDA 93.394) for a five-year Project Grant spanning April 1, 2026 through March 31, 2031. The award supports development and optimization of advanced magnetic resonance (MR) imaging and radiation therapy planning technologies to improve treatment outcomes for patients with primary and secondary liver tumors. Specifically, the research addresses functional avoidance stereotactic body radiation therapy (FA-SBRT) guided by MR multitasking-driven abdominal integrated imaging (MT-AI2), designed to reduce radiation-induced liver disease while maintaining hepatic function and preserving future treatment options such as liver transplantation. The project aims to overcome current clinical limitations in assessing voxel-level liver function and establishing quantifiable metrics for treatment planning through convergence of cutting-edge MR imaging sequences and advanced non-coplanar four-point planning optimization methods. By developing clinically accessible methodologies to spare functional liver tissue while delivering high biologically effective doses to tumors, this research directly responds to NCI priorities in clinical characterization of cancer therapy-induced adverse effects and mechanism-based interventional strategies. The deliverables include development and validation of imaging protocols, quantifiable functional liver metrics, and optimized treatment planning algorithms to reduce toxicity and augment therapeutic outcomes for SBRT patients.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $700.8k | 3/12/26 |