Project Grant R01CA292818

Award Date 6/9/25
Completion Date 5/31/30
Dollars Obligated $619K
Federal Grant Program
93.396
Assistance Type
Project Grant
Place of Performance
California, USA
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This National Cancer Institute (NCI) Project Grant award under CFDA 93.396 - Cancer Biology Research provides $552,874 in funding to The Regents of the University of California, San Francisco (UCSF) from August 1, 2024 to July 31, 2029. The project aims to dissect the cellular and molecular pathways by which the A20 protein regulates anti-tumor immunity. Specifically, the research will focus on understanding how A20, a potent regulator of immune homeostasis, restrains both acute and anamnestic...
This federal Project Grant award of $441,202.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to investigate the role of ex-regulatory T cells (ex-Tregs) in autoimmunity and cancer immunity. The research aims to utilize a genetic Treg lineage tracing system to monitor ex-Tregs and test whether they are required for tumor control or the onset of autoimmune disease when...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $276,450 to The Salk Institute for Biological Studies to investigate the role of the PPARD/CIITA/MHCII axis in regulating regulatory T cell (Treg) function and its impact on tumor immunity. The key objectives are to: 1) define the molecular mechanisms by which MHCII expression in Tregs is regulated by the PPARD/CIITA...
The National Cancer Institute (CFDA 93.396 - Cancer Biology Research) awarded a $571,496 Project Grant to the University of Toledo Health Science Campus Division to conduct research aimed at understanding the mechanisms by which the tumor-intrinsic TAZ expression regulates the tumor microenvironment and immune suppressive cells like myeloid-derived suppressor cells (MDSCs) in triple-negative breast cancer (TNBC). The research project, titled "Dissecting Molecular Mechanisms of Tumor-Induced...
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