This National Cancer Institute (NCI) Project Grant Award under the Cancer Detection and Diagnosis Research program (CFDA 93.394) provides $666,670 to The Trustees of the University of Pennsylvania (Penn) from January 15, 2025 to December 31, 2028. The goal of this project is to develop methods and protocols to obtain high-quality dynamic information from both PET and spectral CT imaging modalities, and use dynamic spectral CT for PET kinetic modeling to reduce overall scan time to match existing clinical PET protocols. The project aims to enhance diagnostic capabilities in oncology, with broad applications in other diseases, while reducing the burden on patients through shorter imaging protocols. Key research activities include developing spectral CT protocols and processing pipelines for input function and perfusion maps, advanced modeling to combine spectral CT and PET data for kinetic modeling, and evaluating PET-spectral CT to quantify blood flow and glucose metabolism in breast cancer. The project will leverage Penn's expertise and research infrastructure to deliver innovative solutions that facilitate the acquisition of high-quality dynamic imaging data for improved oncological diagnostics.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $666.7k | 1/13/25 |