Project Grant R01AT013452
- The National Center for Complementary and Integrative Health awarded University of California Irvine a cooperative agreement for $1,214,743 on August 15, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213). The award funds planning and pilot activities for ACUITY 2, a multi-center Phase 3 randomized controlled trial of acupuncture versus usual care for acute pain management in emergency departments. The planning phase includes three aims:...
- The National Center for Complementary and Integrative Health (NCCIH) awarded the University of Massachusetts Medical School a $297,373 cooperative agreement on August 17, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213). The award funds a Data Coordinating Center (U24) to provide statistical and data management leadership for a multi-center Phase 3 randomized controlled trial (ACUITY 2) examining whether acupuncture is superior to usual care for...
- The National Center for Complementary and Integrative Health, part of the National Institutes of Health within the Department of Health and Human Services, awarded $1,671,750 to the Regents of the University of Michigan on August 11, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to conduct a pilot trial of transcutaneous electrical accustimulation (TEA) for chronic pain management in patients with cirrhosis. The recipient will conduct the...
- The National Center for Complementary and Integrative Health awarded the University of California, San Diego $788,967 on April 16, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to investigate the effects and mechanisms of psilocybin-induced pain relief in chronic phantom limb pain. The research will examine whether and how psilocybin modulates chronic phantom limb pain, a treatment-resistant condition affecting up to 64 percent of the...
- The National Center for Complementary and Integrative Health of the Department of Health and Human Services awarded Southern California University of Health Sciences $535,524 on August 15, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to assess the quality and value of non-pharmacological therapies compared to prescription drug therapy for managing spinal pain in Medicare beneficiaries aged 65 and older. The research will use Medicare...
- The National Cancer Institute awarded the University of Illinois $677,197 on September 1, 2026, under the Cancer Treatment Research program (CFDA 93.395) to conduct a Phase III randomized controlled trial evaluating acupuncture's effects on psychoneurological symptoms in breast cancer survivors undergoing endocrine therapy. The research will compare 10 acupuncture sessions delivered over 6 weeks against sham acupuncture and usual care in a cohort of 252 breast cancer survivors. The trial...
- The National Center for Complementary and Integrative Health (NCCIH), a component of the Department of Health and Human Services National Institutes of Health, awarded $407,856 to Cleveland Clinic Lerner College of Medicine of Case Western Reserve University on August 1, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213). The recipient will conduct research examining how alpha-frequency transcranial alternating current stimulation (tACS) targeting...
- The National Center for Complementary and Integrative Health, part of the Department of Health and Human Services National Institutes of Health, awarded Duke University $444,125 on August 13, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to test the feasibility and acceptability of a psychological support and resource navigator program for orthopedic patients with high-impact chronic musculoskeletal pain. The navigator program addresses the...
- The National Center for Complementary and Integrative Health (NCCIH) at the Department of Health and Human Services awarded The Regents of the University of California, San Francisco $601,259 on April 17, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to assess the multi-site feasibility of an integrated whole-body hyperthermia and cognitive behavioral therapy intervention for major depressive disorder. The award funds a three-site feasibility...
- Federal Cooperative Agreement Summary The National Institute of Neurological Disorders and Stroke awarded a $823,860 Cooperative Agreement to the University of California, Los Angeles on August 15, 2025, to conduct a pragmatic trial evaluating Emotional Awareness and Expression Therapy (EAET) for veterans with chronic pain. The project addresses a significant clinical need, as chronic pain affects approximately one-third of the veteran population and frequently co-occurs with trauma and mental...
The National Institutes of Health National Center for Complementary and Integrative Health awarded $1,322,441 to the University of California, San Diego on August 11, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to conduct a multi-site feasibility study in preparation for a definitive clinical trial randomizing patients with acute pain to battlefield acupuncture, battlefield acupressure, or sham treatment. Acute postoperative pain affects over 40 million annual surgical procedures in the United States, with many cases evolving into persistent pain. Current opioid-based treatment leaves over 80 percent of patients with inadequate pain relief and carries significant risks of misuse, dependence, overdose, and diversion. Battlefield acupuncture requires only a 4-hour certification course and involves inserting 1 to 10 small needles into the ear(s) that remain in place for multiple days, offering a low-cost, accessible analgesic with no systemic side effects or serious medical risks and applicability to nearly all patients. Battlefield acupressure is a needleless variant under consideration. Although tens of thousands of patients are treated with these techniques annually in U.S. military and Veterans Affairs healthcare facilities, and implementation throughout NATO's 31-nation membership is imminent, the efficacy of both techniques remains unclear due to limited, methodologically flawed prior trials. Work is performed at UC San Diego Health in La Jolla, California. The performance period extends through July 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 8/13/26 |