Project Grant R01AR085550
- This $636,198 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to decipher the roles of age and inflammation in intervertebral disc degeneration and low back pain. The University of Miami will conduct a systematic investigation to quantify how aging and inflammatory conditions impact proteoglycan biosynthesis, a key process regulating...
- This federal Project Grant award of $115,301 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846) supports research to investigate the impact of abnormal lipid metabolism on intervertebral disc degeneration in mice. The research will comprehensively assess the mechanical properties of mouse intervertebral discs using in vivo and ex vivo testing systems, after...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $584,330 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846) to Northeast Ohio Medical University (Neomed) to conduct research on the role of mitochondrial DNA leakage in intervertebral disc degeneration and associated inflammation. The project aims to investigate whether oxidative damage to mitochondrial DNA leads to its fragmentation and...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $1,136,924 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to the Rector & Visitors of the University of Virginia. The grant, awarded on July 1, 2025, is intended to support research on "Targeting Stage Specific Influxed Monocytes to Treat Acute and Chronic Back Pain". The project aims to use transgenic mouse models and a CCR2 antagonist to...
- The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a Project Grant of $413,655 on August 1, 2025 to Arizona State University (ASU) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant will fund research to develop biomaterials with temporal control of proteins, such as Bone Morphogenetic Proteins (BMPs), to enhance bone repair. The research aims to mimic natural extracellular matrix interactions and synergies...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846), provides $675,131 in funding to the University of California, San Diego (UCSD) from August 1, 2025 to June 30, 2030. The goal of this project is to develop advanced magnetic resonance imaging (MRI) techniques, including ultrashort echo time (UTE) and adiabatic T1 mapping, to accurately...
- This $219,609 project grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is aimed at developing a method to assess mechanical failure of bone matrix using in vitro cell culture. The primary goal is to overcome the current challenge of requiring whole mouse bone specimens to detect changes in bone matrix mechanical properties, by using micropillars generated from...
- The University of Southern California (USC) received a $628,174 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The purpose of this multi-year grant, with an ultimate completion date of March 31, 2030, is to support research into the cellular origins and molecular mechanisms underlying the development of arthrofibrosis, a debilitating...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $1,037,340 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to The Broad Institute, Inc. to transform the Musculoskeletal Knowledge Portal (MSKKP) into an established biomedical knowledgebase. The project aims to integrate diverse 'omics datasets curated by musculoskeletal research experts, process the data through advanced genetic and genomic analysis...
- This Project Grant award, totaling $176,148.00 and effective from April 1, 2025 to March 31, 2030, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The funding supports a research project led by Dr. Maxime Kinet at the University of California, San Francisco (UCSF) that aims to elucidate the mechanisms by which PI16-expressing fibroblasts, a...
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $703,634 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to The Regents of the University of California, San Francisco (UCSF). The grant, awarded on August 15, 2025, will fund a study to develop and validate age-relative measures of biochemical intervertebral disc health. The research aims to discover the age-course of biochemical disc composition, identify risk factors for early deficits in disc health, and determine whether these biomarkers predict clinical outcomes and future chronic low back pain risk better than conventional imaging methods. UCSF, a prominent academic medical center, will leverage its expertise in neuroscience, musculoskeletal research, and translational studies to execute this 5-year research project, which is scheduled for completion by May 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $703.6k | 8/15/25 |