Project Grant R01AR085315
- This $628,968 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is focused on using innovative biomarker techniques to understand the underlying genetic abnormalities and treatment responses of "PSO-AD" rashes that exhibit overlapping features of both psoriasis and atopic dermatitis. The key objectives are to develop quantitative biomarkers that...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $343,904 to The Regents of the University of California, San Francisco to investigate transcriptional abnormalities in skin-resident T cells as potential biomarkers for atopic dermatitis in Asian and Hispanic genetic backgrounds. The research aims to validate an abnormal atopic T...
- This $397,708 Project Grant awarded by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) aims to advance the treatment of atopic dermatitis (AD) by identifying novel drug targets. The University of California, San Diego (UCSD) is the prime awardee and will utilize an innovative chemical biology platform, Profiling of Active Cutaneous Enzymes (PACE), in conjunction with untargeted lipidomics to investigate enzyme regulation and lipid metabolism...
- This federal Project Grant award of $528,558 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support research to study cellular and molecular features of the immune microenvironment in atopic dermatitis patients receiving the targeted treatment dupilumab. The research aims to better understand mechanisms underlying treatment resistance and paradoxical inflammatory...
- This Project Grant award of $170,490 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support research to develop and validate computable phenotypes for pediatric atopic dermatitis and compare the effectiveness and safety of dupilumab versus methotrexate for treating this condition. The funding will enable The Johns Hopkins University to utilize electronic health...
- This $5,176,858 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research on the role of skin microbiome in the development of allergic diseases like atopic dermatitis (AD) and food allergy (FA). The research aims to analyze approximately 6,000 skin swab samples from a cohort of 2,000 children in the SUNBEAM Early Life Study to identify bacterial strains and genes...
- This $250,396 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846) is focused on unraveling the epigenetic and transcriptional control mechanisms underlying the observed differences in gene expression profiles of skin cells from individuals of different ancestral backgrounds. The research team at the Icahn School of Medicine at Mount Sinai will...
- This federal Project Grant award of $1,901,310.00, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to investigate how skin inflammation drives the development of psoriatic arthritis (PsA). The research, conducted by the University of California, San Francisco, aims to characterize the pathogenic T cells triggered by epidermal immune...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $313,012 to Alleviate Solutions Inc. to refine a novel at-home kit for contact dermatitis testing and diagnosis. The project aims to develop an integrated solution that combines a skin patch test kit, a mobile application for patients and providers, and a cloud-based infrastructure....
- This $169,560 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to expand the understanding of cutaneous opioid circuitry and its function in regulating skin inflammation and sensation. The award recipient, The Regents of the University of California, San Francisco (UCSF), will conduct research to characterize the sources of the endogenous opioid...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will fund research to develop personalized predictive models for the course of atopic dermatitis in diverse global settings. The $243,950 award to the University of California, San Francisco will support a multi-year study to: 1) create prognostic models for persistent atopic dermatitis using early life predictors across cohorts in Uganda, Ecuador, and the UK; 2) evaluate additional predictors like genetics and environmental factors; and 3) expand the models to include comorbidities like allergies, neuropsychiatric conditions, and metabolic disorders. The goal is to provide better prognostic information to improve patient counseling and the efficiency of clinical trials evaluating new atopic dermatitis treatments.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $244.0k | 9/17/25 |