Project Grant R01AR085078
Award Date 9/1/25
Completion Date 8/31/28
Dollars Obligated $1.5M
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
- This Project Grant award of $522,714 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to investigate the role of stretch activation in mammalian skeletal muscle endurance. The research will focus on measuring the characteristics and mechanisms of stretch activation in mouse slow-twitch and fast-twitch muscle fibers, including determining the specific myosin...
- This federal Project Grant award, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support research to elucidate the role of lysine acetylation in regulating skeletal muscle contractile function. The $1,853,872.00 award, spanning from September 15, 2025 to August 31, 2028, will be provided to the University of California, San Diego (UCSD) to investigate how the...
- This federal Project Grant award of $654,388.00 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to elucidate the underlying mechanisms of statin-associated muscle symptoms (SAMSS) and explore potential therapeutic interventions. The principal investigator will leverage access to muscle tissue samples and a mouse model to identify the binding sites of commonly used statins on the ryanodine receptor 1 (RYR1) and evaluate the effects on...
- This $488,575 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will support research to understand how myosin binding protein-C (MYBP-C) regulates skeletal muscle contraction and how mutations in the genes encoding slow and fast MYBP-C (MYBPC1 and MYBPC2) cause congenital skeletal muscle diseases. The research team at the University of Arizona will use...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $198,263 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846) to the Board of Regents of the University of Nebraska. The research project aims to investigate the role of the protein Mitsugumin 53 (MG53) in preventing muscle atrophy during periods of disuse, which can contribute to age-related sarcopenia and frailty. The research will explore how...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $216,113 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to Weill Medical College of Cornell University. The grant funding will support research to target the GDF15-GFRAL signaling pathway to prevent and treat cachexia (muscle wasting) in a mouse model of mitochondrial myopathy. Specifically, the research aims to determine if inhibiting the GDF15-GFRAL...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), is funding research on the role of HOX-expressing interstitial cells in muscle growth, homeostasis, and regeneration. The $557,357 award, effective from March 14, 2025 through February 28, 2030, will support a University of Wisconsin-Madison research project investigating the ability of a...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $352,777 to support research into the regulation of sarcomere growth in skeletal muscle. The research aims to: 1) Identify molecular targets that impact sarcomere addition during muscle growth, and 2) Use in vivo protein tagging methods to study the dynamics of newly synthesized sarcomere...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846), provides $1,622,775.00 to the Van Andel Research Institute (VAI) in Grand Rapids, Michigan to study the critical role of mitochondrial oxidative metabolism in regulating muscle satellite cell fate and function. The research aims to definitively determine the metabolic requirements...
- This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to develop specialized cryo-electron microscopy (cryo-EM) techniques to study the structures of mitochondrial complexes implicated in muscular myopathies. The $444,109 award to the Scripps Research Institute in La Jolla, CA will support the creation of methods to directly visualize endogenous...