Project Grant R01AR084021
- This federal Project Grant award of $371,871.00 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports a biopsychosocial investigation into contemporary human models of postoperative pain. The 5-year project, awarded to the University of Alabama at Birmingham (UAB), aims to gain a deeper understanding of the mechanisms underlying nociception and the pain experience in humans through the perioperative setting of...
- This federal Project Grant award of $451,000.00 from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) supports research on how biological sex and sex hormones modulate chondrocyte mechanotransduction, which may contribute to the higher prevalence of knee articular cartilage degeneration in women compared to men, particularly after menopause. The award was made to The University of Texas Southwestern Medical Center, which will investigate the role of the...
- This $4,649,740.00 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a study to understand inter-individual differences in the clinical trajectory of chronic musculoskeletal pain (CMSKP). The research aims to develop network representations of patients' lived experience of pain and functional state using language models and home-based videos, and to analyze state transitions in...
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $301,304 to the University of Illinois to conduct research on sex-specific musculoskeletal adaptations to wheelchair use in childhood and adolescence. The primary objectives are to: Establish the relationships between sex-specific adaptations to glenohumeral muscle morphology, scapula shape, and...
- The Project Grant award of $205,000 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will support research to elucidate the role of serotonergic and purinergic signaling pathways in mediating nociception (pain sensation) within the female reproductive tract. The award to the University of California, San Francisco (UCSF) will utilize state-of-the-art...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $238,685 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The Regents of the University of California, San Francisco (UCSF). The grant, awarded on August 1, 2025, supports research to elucidate the sex-dependent mechanisms by which regulatory T cells modulate pain sensitivity in a hormone-dependent manner, including investigating the...
- This $453,104 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to explore the role of spinal cord projection neurons in conveying pain signals to the brain. The primary objective is to investigate functional redundancy between two distinct subtypes of spinal projection neurons, those expressing TACR1 (substance P...
- This $2,969,745 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the Drug Use and Addiction Research Programs (CFDA 93.279), supports research to identify neurological mechanisms underlying endometriosis-associated pelvic pain (EAPP) and develop improved treatment approaches. The project synthesizes data from multiple existing studies at the University of Michigan, supplemented by population-based samples, to develop and validate brain-based...
- The Regents of the University of Michigan received a $123,156 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (CFDA 93.865) to conduct research on the neurobiological underpinnings of adolescent chronic pelvic pain. The overarching goal is to map the personalized neural variability underlying reproductive health-related chronic pelvic pain, with the specific aims of: 1) examining personalized neural networks involved in gynecological...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $417,090.00 to the University of Virginia to develop a wireless, soft electronics-enabled smart microneedle patch for managing neck pain. The project aims to integrate electronic devices with thermo-responsive therapeutic microneedles to deliver effective pain relief while avoiding the side effects of oral medications. The funding supports the research and development of this novel transdermal...
This Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) is focused on evaluating mechanical and non-mechanical factors contributing to chronic neck, shoulder, arm, and back pain in full-busted women. The $107,452 award, spanning from September 2025 to August 2029, will be administered by the University of Houston System. The project aims to investigate the influence of factors such as sex hormones, systemic inflammation, and cortical changes in the somatosensory and motor regions on chronic pain manifestation in this population. Additionally, the project will evaluate a non-pharmacological, mechanical intervention to alleviate the pain. This research is intended to address a critical gap in the understanding of physiological and neurological sex differences in chronic musculoskeletal pain experienced by women with larger breast sizes.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $107.5k | 9/15/25 |