Project Grant R35GM159908
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $178,856 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research aimed at developing an interpretable and predictive model for post-surgical pain (P-SP) outcomes. The project will leverage multimodal data, including functional...
- This federal Project Grant award in the amount of $5,057,591 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the award is to conduct a comprehensive, prospective observational study with 2,400 emergency department patients seeking care for acute pain. The study aims to: 1) characterize clinically-informed pain phenotypes, 2)...
- This federal Project Grant award for $667,349.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The award is supporting research conducted by the University of Pennsylvania to investigate the role of endogenous opioid signaling and neural circuits involved in modulating pain perception and placebo analgesia. The research aims to elucidate the...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $9,237,770 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The Washington University to conduct the "IMPETUS: Integrated Mechanisms, Phenotypes, and Translational Underpinnings of Chronic Pain After Surgery" research project. The goal is to gain integrated mechanistic insights into peripheral and central biological processes that contribute to chronic postsurgical pain...
- This $241,401 Project Grant, awarded by the National Science Foundation (NSF) under the Engineering (CFDA 47.041) program, supports the development of in vitro models to better understand the mechanisms driving chronic pain and identify new treatment targets. Specifically, the award will fund the engineering of a physiologically-relevant multi-compartment model of nociceptor hypersensitivity and the establishment of a neuroimmune-specific model to test anti-inflammatory macrophage mechanisms...
- This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on developing novel methods for selectively stimulating nociceptors (pain receptors) and measuring the brain's nociceptive-specific response in both healthy individuals and those with the chronic pain condition fibromyalgia. The $2,314,276 award to Emory University will fund the creation of a new...
- This Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The $226,530 award will support a research project at the University of California, San Francisco (UCSF) focused on using brain stimulation to identify and test network biomarkers for chronic pain relief. The project aims to leverage advanced functional MRI,...
- This Project Grant award of $4,649,740 from the National Institute of Neurological Disorders and Stroke (part of the National Institutes of Health) under the Drug Use and Addiction Research Programs (CFDA 93.279) is funding research to develop network-based models for understanding inter-individual differences in the progression of chronic musculoskeletal pain, using knee osteoarthritis as a case study. The research aims to: 1) Use natural language processing to annotate patient narratives and...
- This $147,486 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to Carnegie Mellon University supports research to identify and target neural subpopulations in the spinal cord that mediate chronic pain. The project aims to analyze the genomic cis-regulatory elements (CREs) of neural subtypes in the macaque and mouse spinal cord to characterize the genetic markers...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of PAIN VITALS, an AI-powered wearable physiological sensor system for continuous and objective monitoring of post-surgical pain. The $349,855 award to Aventusoft L.L.C., a minority-owned small disadvantaged business in Boca Raton, FL, will fund the design, development, and clinical testing of this innovative...
This Project Grant award of $371,871 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will fund a biopsychosocial investigation into contemporary human models of postoperative pain. The project aims to gain a deeper understanding of the mechanisms underlying nociception and the pain experience in surgical patients. Key activities include examining endogenous pain modulation, pain neurocircuitry, blood-based biomarkers, and relevant psychological and social factors associated with the transition from acute to chronic postoperative pain. The award will support this research at the University of Alabama at Birmingham, a prominent public research institution with expertise in biomedical research and federal grant and contract portfolio. The project will run from September 1, 2025, through August 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $371.9k | 8/25/25 |