Project Grant R01AI201310
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The University of Texas Southwestern Medical Center $451,000 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period (August 1, 2025 – July 31, 2027). This Project Grant supports basic biomedical research investigating how prenatal exposure to maternal helminth (parasitic worm) infections alters immune programming in offspring, with potential...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant of $822,060 on May 11, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on maternal respiratory infection and fetal lung development. The award supports a five-year research initiative (completion date: April 30, 2031) investigating how maternal Severe Acute Respiratory Syndrome Coronavirus 2...
- Federal Grant Award Summary Seattle Children's Research Institute received a $3.61 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 14, 2025, with a completion date of June 30, 2029. This research project investigates hyaluronidase (HylB), a virulence factor produced by Group B Streptococci (GBS), to elucidate mechanisms by which the enzyme suppresses immune...
- Federal Project Grant Award Summary Drexel University received a $416,199 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025 through June 30, 2027. The award supports biomedical research investigating the immunomodulatory effects of interferon lambda on infant neutrophils in the context of influenza viral infection. The research employs a neonatal murine...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $802,421 to the University of Pittsburgh under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 8, 2026, for a prospective cohort study examining maternal Respiratory Syncytial Virus (RSV) vaccine durability and infant protection. The research project, scheduled for completion by May 31, 2031, will deliver immunological and serological analyses across two...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the Regents of the University of Minnesota a $2,999,774 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on maternal microbial exposure and CD8 T cell populations at the maternal-fetal interface (MFI). The award, obligated on July 17, 2025, with a completion date of June 30, 2029, funds fundamental immunological research that...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of South Florida a $791,245 Project Grant effective May 6, 2026, through the Allergy and Infectious Diseases Research program (CFDA 93.855) to support fundamental biomedical research on placental antiviral defense mechanisms. The research, conducted through a collaborative effort between the Totary-Jain and Coyne laboratories, will elucidate how human trophoblasts (placental barrier cells) produce Type III...
- Federal Grant Award Summary The University of Michigan received a $411,078 Project Grant awarded April 7, 2026, by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award funds research through March 31, 2028, conducted at the institution's Ann Arbor, Michigan campus. The project investigates how perinatal exposure to diverse pathogenic microbes influences the development and functional programming of...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $836,132 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Magee-Womens Research Institute and Foundation on June 17, 2026, with a completion date of May 31, 2031. The grant funds biomedical research investigating how maternal antibiotic exposure during pregnancy disrupts the production and microbial specificity of secretory immunoglobulin A...
- Federal Grant Award Summary Michigan State University, in partnership with Henry Ford Health, received a $217,698 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) awarded July 3, 2026, with completion targeted for June 30, 2028. The award funds research aimed at understanding papillomavirus pathogenesis in WHIM (Wiskott-Aldrich Syndrome-like Immunodeficiency) syndrome and developing...
Grant Summary Wayne State University's Sponsored Project Administration Division received a $514,261 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 13, 2026, with a completion date of June 30, 2031. The award funds research investigating how maternal viral infection during pregnancy alters offspring immune function through hematopoietic stem cell (HSC) reprogramming mediated by placental inflammasome signaling. The research will examine sex-specific differences in offspring susceptibility to bacterial infections postnatally, focusing on neutrophil function impairment and lipopolysaccharide (LPS) hypersensitivity, particularly in male offspring. The project will deliver three primary research products: (1) characterization of fetal and offspring HSC fate trajectories, function potential, and transcriptional and epigenetic signatures following maternal viral infection; (2) identification of placental signaling pathways—specifically interleukin-1 (IL-1) mediated pathways—driving sex-specific offspring HSC immune reprogramming; and (3) mechanistic insights into the origins of IL-1 production in response to viral exposure. These outputs will contribute to the broader goal of developing preventive and therapeutic strategies to improve offspring immunity against infections, advancing the scientific understanding of long-term immune consequences of prenatal viral exposure.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $514.3k | 7/13/26 |