Project Grant R01AI200088
- This federal Project Grant award of $430,375.00 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research at Emory University on a novel inter-membrane lipid signaling mechanism in Gram-negative bacteria. The research aims to understand how bacteria maintain the lipid asymmetry of their outer membrane, which is critical for survival, virulence, and antibiotic resistance. Specifically, the project will investigate how...
- The federal Project Grant award of $778,829.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research conducted by Emory University to characterize early-life B-cell and antibody-secreting cell development and function in the human spleen, in order to uncover mechanisms of adaptive immunity at birth. Key objectives include understanding the differences between...
- This federal Project Grant award of $112,956.00 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research at Texas A&M University System Health Science Center to define the role of sex-specific traits in influencing the integration of immune and metabolic responses that impact infection susceptibility. The research will use the Drosophila melanogaster model to test the hypothesis that post-mating changes in...
- The U.S. National Institute of Allergy and Infectious Diseases (NIAID) awarded a $439,088 Project Grant under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH). The project, led by Principal Investigator Dr. Daniel Lingwood, aims to mechanistically define how sex differences in hormones and circulating cytokines modulate B cell class switch recombination, a core immune...
- This Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research grant program (CFDA 93.855). The $684,627 award to Georgia State University Research Foundation Inc. supports research to investigate how the sexually transmitted pathogen Neisseria gonorrhoeae (N. gonorrhoeae) interacts with host cell glycans to facilitate nutrient acquisition and infection. The project aims to understand the role of conserved...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $450,766 to the University of Virginia to conduct research on the mechanisms by which the bacterium Chlamydia trachomatis modulates host cell organelles and inter-organelle communication to establish an intracellular replication niche. The research aims to provide a holistic understanding of how Chlamydia infection disrupts normal organelle...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to characterize the role of interferon epsilon in protecting against Trichomonas vaginalis, a common sexually transmitted infection, and how the parasite's extracellular vesicles suppress this host immune response. The $159,600 award to Creighton University will fund this 2-year research project from August 2025 to July 2027....
- This federal Project Grant award of $705,557 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to better understand the coordination of innate and cellular mucosal immunity in SARS-CoV-2 clearance. The primary objectives are to determine the contribution of monocytes in promoting T cell responses and viral control within the respiratory tract, and to define the effector mechanisms of...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $243,750 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Wisconsin-Madison. The grant supports research to investigate how the bacterium Gardnerella promotes the pathogenesis of Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection gonorrhea. The project aims to determine the mechanisms by which two Gardnerella virulence factors,...
- This federal Project Grant award of $913,012 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to investigate the mechanisms underlying the increased prevalence of "Long COVID" in women compared to men. The primary objectives are to: Measure persistent SARS-CoV-2 infection, type I interferon responses, adaptive immunity to SARS-CoV-2 and other persistent viruses, autoantibody production, and...
This $2,112,000 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to Emory University supports research on understanding the impact of menstruation on cellular immunity against chlamydia and gonorrhea infections. The project aims to elucidate how the immune-mediated tissue remodeling process of menstruation compromises the immune response to these common sexually transmitted bacterial pathogens. The research will focus on developing long-lived resident memory T cells in the female reproductive tract to enhance immunity and accelerate bacterial clearance, which could inform the development of more effective vaccines against these infections. The project period runs from Sep 2025 to Aug 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.1m | 9/22/25 |