Project Grant R21AI193265
Award Date 8/8/25
Completion Date 7/31/27
Dollars Obligated $451K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Virginia, USA
Similar Awards
- This Project Grant award of $782,795.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to investigate the mechanisms regulating the division process of the bacterium Chlamydia trachomatis, the leading cause of bacterial sexually transmitted infections. The award, with a project period from June 17, 2025 to May 31, 2030, aims to advance the understanding of how this intracellular...
- This Project Grant award of $145,745 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate how the bacterium Chlamydia trachomatis modulates the host immune response and inflammasome activation. The research aims to understand the mechanism by which a specific Chlamydia protein, CT226, interacts with host proteins LRRFIP1 and FLII to regulate inflammasome activation during...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) in the amount of $130,950 to the Regents of the University of Idaho to conduct research on understanding the regulation of gene expression and the function of type III secretion system translocons in the developmental cycle of chlamydial bacteria. The research aims to provide a more complete understanding of the chlamydial developmental cycle, which...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research grant program (CFDA 93.855), provides $156,000.00 to support research on characterizing the process of homotypic fusion in the Chlamydia muridarum (CM) bacterial species. The research aims to understand how this fusion process contributes to the virulence and pathogenesis of Chlamydia infections, a leading cause of sexually transmitted...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), provides $431,750 to the University of California, Irvine (UCI) from August 1, 2025 to July 31, 2027. The project aims to develop new complementation tools to enhance the rigor of genetic approaches used to study the function of genes in the Chlamydia trachomatis bacteria, which causes over 1.6 million reported...
- The University of Kentucky Research Foundation was awarded a $423,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research CFDA program. The funding will support a 2-year research project to investigate the role of chlamydial polymorphic membrane proteins (PMPs) in the pathogenesis of Chlamydia trachomatis infections, which cause a variety of acute and chronic diseases. The project aims to delineate the specific...
- This federal Project Grant award, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand how the menstrual cycle and associated immune changes impact the development of chlamydia and gonorrhea infections in women and adolescent girls. The $2,112,000 grant was awarded to Emory University on September 22, 2025, with a final completion date of August 31, 2029. The...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) program, provides $244,870 to the University of Washington to evaluate vaccination and antibiotic prophylaxis strategies for preventing Chlamydia trachomatis (CT) infections at the population level. The project aims to 1) assess the frequency and characteristics of antibiotic use among individuals eligible for prophylaxis, and 2)...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), is funding research to investigate the mechanisms by which bacterial cholesterol-dependent cytolysins (CDCs) activate the NLRP3 inflammasome, a key innate immune signaling complex responsible for triggering inflammation. The $506,394 award, effective from January 24, 2025 through December 31, 2029, will support studies using...
- The Applied Research Foundation of West Virginia received a $444,000 Project Grant from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research program) to study the effects of stress on Chlamydia infections in a mouse model. The research aims to define the mechanisms by which stress may suppress the immune system and increase the intensity of Chlamydia genital infection and its associated immunopathologies. Key aspects of the project...