Project Grant K22AI189595
Award Date 8/15/25
Completion Date 7/31/27
Dollars Obligated $160K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Omaha, NE 68178, USA
Similar Awards
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $153,568 to the University of California, Los Angeles (UCLA) to conduct research on the role of interferon epsilon (IFNε) in the immune response against the protozoan parasite Trichomonas vaginalis. The research aims to: 1) determine which steps in the IFNε-mediated type I interferon response are blocked by...
- This $570,760 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The grant supports a multidisciplinary research project to study the structure and function of intraflagellar transport (IFT) in the trypanosomatid parasite Leishmania, which causes several major human diseases. The research aims to elucidate the conserved and parasite-specific features of Leishmania...
- This federal Project Grant award, valued at $2,297,892.00 and provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate the mechanism by which interferon-induced transmembrane proteins (IFITMs) inhibit the fusion of diverse enveloped viruses with host cells. The research aims to elucidate the ultrastructural basis for IFITM-mediated inhibition of viral fusion,...
- This Project Grant award was provided by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), to the University of California, Irvine (UCI). The $471,159 grant supports research to elucidate the mechanisms of local axonal responses to interferon lambda (IFN-L) and their effects on the invasion of the nervous system by alpha herpesviruses, such as herpes simplex virus-1 (HSV-1). The research aims to...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $817,730 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Vermont & State Agricultural College. The grant, awarded on July 9, 2025, supports the development of new tools to study how the Toxoplasma gondii parasite delivers its "effector" proteins into host cells during the invasion process. This research aims to understand the mechanisms by which T....
- This $114,546 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support research to investigate the role of type 1 interferon signaling on vaccine stability within lymphatic endothelial cells. The project aims to (1) determine if the type 1 interferon response in lymphatic endothelial cells promotes antigen archiving and enhances protective immunity, and (2) examine how type 1...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $518,400 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The New York Structural Biology Center, Inc. (NYSBC) to determine the three-dimensional structure of a unique bipartite internal ribosome entry site (IRES) from the Giardia lamblia virus (GLV). This IRES violates the typical paradigm for viral IRES elements, as a significant portion resides within the coding region. The...
- This $769,414 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research on how the cellular protein SAMHD1 regulates HIV-1 innate immunity and viral gene expression in primary macrophages. The long-term goal is to define the functional roles and molecular mechanisms of SAMHD1 in regulating innate immunity during persistent HIV-1 infection of macrophages. The research...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), provides $479,925 to support research on the mechanisms by which HIV-1 infection induces the production of type I interferons (IFNs) in human immune cells. The project aims to investigate whether cell-to-cell transmission of HIV-1, rather than cell-free viral infection, is a key driver of IFN activation through...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $435,875 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of California, Merced. The grant, titled "Interrogating NFKBID Dependent Humoral Immunity to Toxoplasma gondii", seeks to understand the mechanisms by which the transcriptional regulator IKBNS (encoded by NFKBID) mediates protective immunity against the parasitic infection Toxoplasma gondii. The...