Project Grant R01AI199896
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Columbia University $239,135 on August 11, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and validate a magnetics-based platform for high-speed mapping of tissue mechanical properties. The project, which will be conducted in New York and is scheduled for completion by July 31, 2027, addresses a critical technical limitation in understanding how...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Columbia University's Health Sciences Division a $452,375 Project Grant (CFDA 93.855: Allergy and Infectious Diseases Research) effective February 6, 2026, through January 31, 2028. The award supports clinical and translational research focused on in vivo profiling of Chimeric Autoantibody Receptor T Cell (CAART) therapy for Muscle-Specific Tyrosine Kinase (MuSK) myasthenia gravis. The...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Trustees of Columbia University in the City of New York a Project Grant totaling $764,591 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a five-year research project running from August 1, 2025, through July 31, 2030. This research initiative investigates the differential regulation of cell cycle entry and apoptosis in cytolytic lymphocytes, specifically...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $515,387 to The Trustees of Columbia University in the City of New York (Health Sciences Division) on August 11, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, titled "Elucidating How Long 3'UTRs Form and Cause Autoinflammation," will be conducted through July 31, 2030, at Columbia University's facilities in...
- Federal Grant Award Summary New York University School of Medicine received a $755,801 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 3, 2026, with completion targeted for January 31, 2031. The award supports investigator-initiated biomedical research examining the regulation of CD4+ and CD8+ T cell function by the protein CLNS1A. The research deliverables...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Columbia University $540,818 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 6, 2025, for a five-year project concluding July 31, 2030. This Project Grant supports fundamental research investigating the interdependency of chemical, structural, and physiological heterogeneity in Pseudomonas aeruginosa biofilms. The research addresses how bacteria survive in...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Columbia University's Health Sciences Division a Project Grant of $452,375.00 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the role of tissue-resident T cells in osteoarthritis and their contribution to inflammatory arthritis induced by immune checkpoint inhibitors (ICIs). The research, conducted in New York, NY, is scheduled from February 13, 2026,...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $508,500 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to New York University School of Medicine, with an award date of April 22, 2026, and a completion date of March 31, 2031. This research grant supports biomedical investigation into the molecular mechanisms by which innate immune cells, specifically neutrophils and professional phagocytes,...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3.14 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Trustees of Columbia University in the City of New York, Health Sciences Division, for research on regulatory T cell (Treg) memory in human tissues. The award, obligated on February 6, 2026, with completion targeted for January 31, 2030, supports fundamental immunology research...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Columbia University's Health Sciences Division a Project Grant of $761,840 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 5, 2025, with a completion date of July 31, 2030. This award supports research to characterize and functionally evaluate plasma cell infiltrates in cardiac allograft vasculopathy (CAV), the leading cause of morbidity and mortality...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded Columbia University's Health Sciences Division a $821,367 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period May 1, 2026 through April 30, 2031. The award funds systematic research to advance understanding of genetic diseases of the immune system (GDIS) through functional variant mapping and precision medicine development. The project will employ massively parallel CRISPR-based editing frameworks to functionally characterize variants of uncertain significance in primary human T cells, utilizing Activated PI3KD Syndrome (APDS) as a model disease. Research activities will include forward saturation screens to identify novel gain-of-function and loss-of-function variants, assessment of drug sensitivity to FDA-approved PI3KD inhibitors, identification of drug-resistant variants, and evaluation of precision combination therapies. The project supports translational research objectives by clarifying the relationship between genetic variants, dysregulated cellular signaling pathways, and clinical phenotypes across molecular, individual, and population levels. Through immunophenotype wide association studies and pathway convergence analysis, the work aims to identify therapeutic targets applicable to multiple GDIS conditions and reduce diagnostic ambiguity associated with variants currently classified as having uncertain significance. The research is designed to generate functional genomic data and therapeutic insights that advance precision medicine approaches for immune system disorders.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $821.4k | 4/28/26 |