Project Grant R01AI198742
- The National Institute of Allergy and Infectious Diseases awarded $431,750 to the University of California Irvine on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855, Assistance Listing Project Grant R21AI199644). The award funds development and validation of a hydro-meteorological malaria model designed to improve forecasts of malaria risk in Africa and to inform tailored vector control strategies adapted to varying environmental and epidemiological...
- The National Institute of Allergy and Infectious Diseases awarded the University of California Irvine $783,811 on July 23, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to optimize pyrroloiminoquinone alkaloid scaffolds as antimalarial and antibabesial clinical candidates. The research program aims to develop novel chemical classes for treating malaria caused by Plasmodium falciparum and babesiosis caused by Babesia species, addressing drug resistance in...
- The National Institute of Allergy and Infectious Diseases awarded the University of California Irvine $823,548 on May 11, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop antimalarial and antibabesial clinical candidates based on leelamine isonitrile (GB-79). The research program will evaluate the biological activity, pharmacological properties, and mechanism of action of GB-79 and its analogues against Plasmodium falciparum and Babesia species, the...
- The National Institute of Allergy and Infectious Diseases awarded The Regents of the University of California, San Francisco $246,000 on May 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to quantify the contribution of malaria infections imported by agricultural populations to transmission dynamics and antimalarial drug resistance spread in Eswatini. The award funds two specific aims: improving case classification using high-resolution genomic data to...
- The National Institute of Allergy and Infectious Diseases awarded the University of California Irvine $196,250 on August 13, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to examine the vectorial capacity of invasive Anopheles stephensi mosquitoes in Ethiopia. The project investigates vector competence of invasive An. stephensi for local Plasmodium falciparum and P. vivax isolates and determines malaria vectorial capacity under field conditions in Ethiopia. An....
- The National Institute of Allergy and Infectious Diseases awarded the University of California, San Diego $480,000 on September 16, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the molecular basis for arboviral fitness in vector and reservoir hosts. The research examines how arboviruses replicate across evolutionarily distant hosts—insects and vertebrates—despite showing high specificity in their transmission cycles. Using alphaviruses as a...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $451,000 to the University of California, San Francisco under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 15, 2025, with completion scheduled for July 31, 2027. This Project Grant supports the development and application of high-resolution phage immunoprecipitation sequencing (PhIP-Seq) arrays designed to comprehensively evaluate antibody responses to...
- The National Institute of Allergy and Infectious Diseases awarded the University of South Florida $203,060 on April 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the ecology and transmission dynamics of Plasmodium malariae in Cameroon. The research will assess the spatial distribution and seasonal trends of P. malariae in Bangolan, a lakeshore area in Cameroon's northwest region, through molecular surveillance conducted via repeated...
- The National Institute of Allergy and Infectious Diseases awarded Kansas State University $738,183 on July 20, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to characterize the immunoregulatory protease network that controls melanization in Anopheles gambiae, the African malaria mosquito vector. The research identifies molecular interactions that regulate phenoloxidase activation and melanization cascade proteases, with the objective of understanding how protease...
- The National Institute of Allergy and Infectious Diseases awarded Iowa State University $578,956 on July 13, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support research on the regulation of axoneme assembly during Plasmodium falciparum gametogenesis, a study aimed at advancing malaria vaccine development. The project, designated R01AI195769, runs through June 30, 2031, with work performed in Ames, Iowa. The research addresses the mechanisms of flagellar...
The National Institute of Allergy and Infectious Diseases awarded the University of California Irvine $667,643 on August 20, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop a malaria intelligence system and mobile decision-support application for malaria prevention and control in Kenya. The project addresses insecticide-resistant mosquito populations and outdoor biting behavior that have emerged from widespread use of long-lasting insecticide-treated nets and indoor residual spraying across Africa. The system will leverage high-resolution satellite data, vector and disease incidence data, and data analytics to enable locally tailored malaria control strategies that account for regional variations in vector ecology and malaria risk, replacing uniform, one-size-fits-all approaches with adaptive, location-specific interventions. Work is performed in Irvine, California, with a period of performance extending from August 20, 2026, through July 31, 2031. This is a Project Grant, a standard assistance type under the NIH's competitive research grant program for biomedical research in infectious disease.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $667.6k | 8/20/26 |