Project Grant R01AI198604
- Federal Project Grant Award Summary Tufts University School of Medicine received a $453,750 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2027. The grant funds research to investigate mechanisms by which bacteriophages evade cyclic oligonucleotide-based antiviral defense systems in bacteria, with specific focus on how phage proteins antagonize...
- FEDERAL GRANT AWARD SUMMARY The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Florida a Project Grant totaling $741,023 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective June 1, 2026, through May 31, 2031. The award funds development of VIGOR (Vibrio Infection Genomics for Outbreak Risk Forecasting), a satellite-based public health forecasting system designed to identify and monitor high-risk zones for pathogenic Vibrio...
- Federal Grant Award Summary The University of Florida's Division of Sponsored Research received a $137,064 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 25, 2025. The two-year project, concluding June 30, 2027, delivers novel conceptual frameworks and computational models to measure and validate dynamic accessibility to healthcare using system science approaches. The primary...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $395,692 to the University of California, San Diego under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 17, 2025, for a project entitled "Enhancing Bacteriophage Function with Coevolution and Synthetic Biology." The award supports a five-year research initiative (through June 30, 2030) focused on identifying genetic modifications in bacteriophages that...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Florida a $1,348,845 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 13, 2026, with completion targeted for January 31, 2031. This research initiative investigates potassium (K+) channel regulation of antiviral immune responses, specifically examining how ATP-gated inward rectifier potassium (KATP) channels modulate...
- Federal Project Grant Award Summary The University of South Florida received a $470,953 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2030. This five-year research initiative will produce biomedical research and scientific knowledge concerning the role of SSR42, a regulatory RNA molecule, in virulence factor regulation and pathogenic...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Florida a Project Grant of $3.39 million under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on ATPase chromatin remodeling complexes as modulators of Human Immunodeficiency Virus (HIV-1) latency and therapeutic targets. The award, effective June 18, 2026, through May 31, 2030, supports research conducted at the university's...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $109,476 to the University of Wisconsin-Madison under the Allergy and Infectious Diseases Research program (CFDA 93.855) on November 30, 2025, with a completion date of May 31, 2027. This Project Grant supports fundamental research to understand the molecular mechanisms governing drug efflux in bacterial multidrug resistance transporters, specifically the NorA pump. The research...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, College Park a Project Grant totaling $571,412 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 11, 2026, with a completion date of May 31, 2031. This five-year research project investigates the role of linear diribonucleotides as signaling molecules in bacterial physiology and pathogenesis. The research builds upon prior findings...
- Federal Grant Award Summary The University of Florida's Division of Sponsored Research received a $422,125 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 3, 2026, with completion targeted for January 31, 2028. This proof-of-concept study will develop, validate, and field-test wastewater-based epidemiology (WBE) methods using digital polymerase chain reaction (PCR)...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Florida a Project Grant totaling $750,263 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 4, 2026, with a completion date of May 31, 2031. This research initiative investigates the complex interactions between bacteriophages (viral predators), bacterial pathogens (prey), and antibiotics in diarrheal disease progression and antimicrobial resistance (AMR) emergence. The project utilizes existing clinical cohorts comprising over 2,000 patients in Bangladesh and a time-series study of 500 patients to validate preliminary findings that effective phage predation correlates with decreased disease severity and increased pathogen genetic diversity, while ineffective predation associates with increased severity and phage genetic diversity. The research deliverables include validation of the phage predation theory across multiple high-priority enteric pathogens including Shigella species and enterotoxigenic Escherichia coli (ETEC), beyond the initial cholera model; characterization of phage resistance factors genetically linked to antibiotic resistance genes on mobile genetic elements; and determination of phage predation's association with AMR emergence within individual patients. The project leverages previously funded NIH and Wellcome Trust research resources and generates scientific knowledge intended to improve understanding of disease mechanisms and inform more effective antimicrobial stewardship strategies addressing the global public health challenge of inappropriate antibiotic use in diarrheal diseases.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $750.3k | 6/8/26 |