Project Grant R01AI193061
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $794,183 to the Beckman Research Institute of the City of Hope on April 8, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support a five-year research project extending through March 31, 2031. The project focuses on investigating the role and regulation of methylarginine effector Tudor Domain-Containing Protein 3 (TDRD3) in T cell immunity. Research...
- Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Beckman Research Institute of the City of Hope a Project Grant of $489,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 5, 2026 through January 31, 2028. This biomedical research grant supports investigator-initiated research aimed at identifying and characterizing novel molecular pathways that regulate inflammatory responses, with specific focus on...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $659,663 to the Beckman Research Institute of the City of Hope under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 1, 2025, for a five-year project period concluding July 31, 2030. The grant supports fundamental research investigating the role of RNA modification in the development and function of invariant natural killer T (iNKT) cells, specialized...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $201,744 Project Grant on June 4, 2026, to The Regents of the University of California, San Francisco, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This five-year research initiative, scheduled for completion by May 31, 2031, will advance understanding of thymic T cell tolerance mechanisms relevant to autoimmune disease diagnosis and treatment. Dr....
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3.1 million Project Grant to the University of California, Los Angeles under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 16, 2025, with a completion date of June 30, 2029. This award funds research to evaluate the mechanisms underlying immunosuppression induction and maintenance impacts on T cell function following kidney transplantation. The research employs...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded J. David Gladstone Institutes a $3.6 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 6, 2026, through January 31, 2030. This award supports investigator-initiated biomedical research aimed at elucidating the transcriptional and post-transcriptional regulatory mechanisms governing regulatory T cell (Treg) identity and stability....
- Federal Project Grant Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $566,875 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the La Jolla Institute for Immunology, with performance in La Jolla, California. The award, dated February 18, 2026, with a completion date of January 31, 2028, supports research to identify and characterize a novel orphan G-protein coupled receptor (GPCR) expressed by tissue-resident memory...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Beckman Research Institute of the City of Hope a Project Grant totaling $932,172.00 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period April 1, 2026 through March 31, 2031. The award funds development of a novel pentavalent circular RNA (circRNA)-based Epstein-Barr virus (EBV) vaccine designed to address the significant public health burden of EBV...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $427,625 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Maryland, Baltimore, effective August 1, 2025, through July 31, 2027. This award funds basic biomedical research investigating CD27-mediated immune suppression mechanisms in hematopoietic stem and progenitor cells (HSPCs), innate immune cells, and non-hematopoietic cells. The...
- Federal Grant Award Summary Columbia University's Health Sciences Division received a $3.14 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 6, 2026, with completion targeted for January 31, 2030. The grant funds investigator-initiated biomedical research examining regulatory T cell (Treg) memory responses in human tissues. The research leverages an established...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded $888,941 to the Beckman Research Institute of the City of Hope on June 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct investigator-initiated biomedical research on thymic regeneration and immune reconstitution following hematopoietic cell transplantation. The five-year project, extending through May 31, 2031, will investigate the role of regulatory T cells (Tregs) and their secreted factors—specifically amphiregulin (AREG) and trefoil factor 1 (TFF1)—as mediators of T cell and thymic epithelial cell regeneration after allogeneic hematopoietic cell transplantation (allo-HCT). This research addresses a significant clinical need to mitigate thymic injury and lymphopenia in transplant recipients and cancer therapy patients. The project will utilize preclinical models to evaluate how Treg-derived regenerative factors facilitate thymic recovery and immune reconstitution, with the ultimate objective of developing therapeutic strategies to enhance thymic function and reduce graft-versus-host disease, malignancy risk, and mortality in allo-HCT recipients. The research is being conducted at the Beckman Research Institute's facility in Irwindale, California, and represents the Institute's continued participation in NIH-funded translational and basic science research addressing complex immunologic and infectious disease mechanisms.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $888.9k | 6/3/26 |