Project Grant R01AI191507
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $230,808 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University in St. Louis, Missouri. The funding will support research to identify heme-binding proteins in the malaria parasite Plasmodium falciparum and investigate their role in maintaining heme homeostasis. The project aims to better understand how the parasite detoxifies heme, an essential but redox-active...
- The Project Grant award of $806,693.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports a research project at New York University (NYU) titled "LYMPHATIC CONTROL OF GERMINAL CENTERS." The project aims to investigate the role of the lymphatic vasculature in regulating immune responses, with a focus on understanding how lymphangiogenesis (growth of new lymphatic vessels) shapes...
- This federal Project Grant award of $791,864 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to identify molecular factors controlling chromatin organization and gene regulation in the malaria parasite Plasmodium falciparum. The research aims to elucidate the importance of long non-coding RNAs (lncRNAs) in parasite development, virulence, and sexual differentiation, with the goal...
- The University of Washington received a $458,849 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct research aimed at uncovering the sensory mechanisms mosquitoes use to detect blood. The project seeks to leverage emerging single-cell RNA sequencing and high-throughput genetic analysis approaches to deeply characterize the diversity of sensory neurons in the mosquito labrum (feeding structure) and...
- This $570,760 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The grant supports a multidisciplinary research project to study the structure and function of intraflagellar transport (IFT) in the trypanosomatid parasite Leishmania, which causes several major human diseases. The research aims to elucidate the conserved and parasite-specific features of Leishmania...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $497,136 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Sloan-Kettering Institute for Cancer Research. The grant supports research to investigate the role of mast cells in regulating the inflammatory pathology of secondary lymphedema, a chronic and debilitating condition that commonly occurs following cancer treatments. The research aims to better understand the underlying...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $155,686 Project Grant to Baylor College of Medicine under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855) to optimize Strongyloides testing in an at-risk U.S. population. This project aims to address the public health challenge of strongyloidiasis, a parasitic infection that can cause severe disease in immunosuppressed individuals. The research will focus on improving diagnostic...
- This $633,218 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research CFDA Program (93.855), supports research to characterize the mechanism of inhibition of the cholesterol transporter protein Pfncr1 in the malaria parasite. The research aims to use structural, physiological, genetic, and cell biological approaches to investigate two new inhibitors of Pfncr1 that are predicted to bind away from the...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $107,542 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University in Missouri. The grant, effective September 1, 2025 through August 31, 2027, aims to unravel the mechanisms underlying the differential sorting and trafficking of Plasmodium falciparum secreted proteins during the symptomatic stage of malaria. The research seeks to determine how exported proteins...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant titled "Role of Tryptophan Catabolism and AHR Pathways in Natural Resistance of Leishmania (Viannia) panamensis to Antimonial Drug" to the University of Maryland, College Park on September 24, 2025. The $193,733 award supports research to investigate the resistance of the Leishmania (Viannia) panamensis parasite, a major cause of cutaneous leishmaniasis in Colombia, to antimonial drugs. The...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $777,360 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University to advance research on lymphatic filariasis (LF) elimination. The project aims to leverage genomic epidemiology to monitor the number of reproductively active adult parasites, differentiate new and established maternal parasite lineages, and understand the drivers of LF resurgence in areas that have reached elimination targets. This 5-year project, commencing on August 1, 2025, will employ comprehensive full-genome analysis of individual microfilariae samples to provide critical insights into LF transmission dynamics and inform strategies to achieve the World Health Organization's LF elimination goals.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $777.4k | 7/25/25 |