Project Grant R01AI187414
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $721,721 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of California, Los Angeles (UCLA). The grant will fund the UCLA RAPID, RIGOROUS, RELEVANT IMPLEMENTATION SCIENCE HUB to provide technical assistance, coaching, and consultation to support implementation science research projects focused on improving HIV outcomes. Over the 5-year period from August 1, 2025...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $451,956 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to Baylor College of Medicine in Houston, Texas. The grant, titled "Exploring T. Pallidum Pathogenesis in the Placenta Using Novel In Vitro Models of Syphilis During Pregnancy", will support research to investigate mechanisms by which the syphilis-causing bacteria Treponema pallidum invades and...
- The University of California, Los Angeles (UCLA) was awarded a $653,677 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The grant, titled "Ongoing Dynamic Choice to Address HIV Treatment Interruption in Malawi (CHOICE)," will implement a cluster randomized control trial to test the impact of a long-term, dynamic choice intervention on 12-month viral suppression for HIV patients in Malawi experiencing...
- This Project Grant award of $426,625 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to assess the feasibility of using the Dual Path Platform (DPP) Syphilis TNT (Treponemal and Non-Treponemal) assay for longitudinal evaluation of syphilis treatment response and reinfection. The primary goal is to correlate the quantitative results from the assay's microreader with...
- This $463,615 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports a short-term exploratory study investigating virologic failure on long-acting antiretroviral therapy (LA-ART) with cabotegravir and rilpivirine. The key objectives are to: 1) assess cabotegravir/rilpivirine concentrations among persons experiencing virologic failure on LA-ART, and 2) evaluate viral resistance mutations using standard...
- This Project Grant award of $445,250, provided by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to Rutgers, The State University of New Jersey, aims to establish a mouse model of congenital syphilis (CS) and determine changes in the host immune response. The project will lay the foundation for developing diagnostics and vaccines for syphilis, a sexually transmitted disease with increasing global incidence. Key objectives...
- The University of Connecticut Health Center (UCHC) was awarded a $457,875 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The grant funding supports research to investigate fundamental aspects of syphilis disease pathogenesis, focusing on nutrient acquisition and environmental sensing mechanisms of the bacterium Treponema pallidum. Key objectives include phenotypically...
- This Project Grant award, totaling $448,150.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The purpose of the grant is to explore how the syphilis-causing bacteria Treponema pallidum avoids complement-mediated killing by recruiting the host's Factor H protein, which could lead to new strategies for controlling syphilis, a persistent global public health concern. The...
- The University of California, Los Angeles (UCLA) was awarded a $415,876 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) by the National Institutes of Health Office of the Director, with a performance period from August 1, 2024 to July 31, 2026. The purpose of this grant is to optimize and utilize a novel five-dimensional (5D) magnetic resonance spectroscopic imaging (MRSI) technique called "ROSE-JRESI" and three-dimensional myelin water imaging (MWI) to study...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $485,375 Project Grant to the University of Washington (UW) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The project, titled "Elucidating the Contribution of Genetic Recombination in Treponema Pallidum to Syphilis Pathogenesis," aims to identify the genes involved in homologous recombination (HR) in the syphilis-causing bacteria Treponema pallidum and examine genomic...
The University of California, Los Angeles (UCLA) received a $627,699 project grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct a randomized clinical trial evaluating antimicrobial prophylaxis for preventing syphilis during pregnancy in high-risk patients in Rio de Janeiro, Brazil. The project aims to enhance serologic screening and utilize point-of-care testing to reduce the incidence of syphilis in pregnancy and congenital syphilis, which have seen a dramatic resurgence in Brazil. The 5-year project, running from August 2025 to July 2030, leverages UCLA's longstanding collaboration and research expertise in the field of infectious disease transmission and prevention, as well as its established research site in Brazil.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $379.9k | 8/27/25 | ||
| Not listed | $247.8k | 8/25/25 |